Study Activation

Main Content Registration


  • is a web-based resource that provides the public with easy access to information on publicly and privately supported clinical studies on a wide range of diseases and conditions.


  • The responsible party must register all applicable clinical trials (ACT) on, update the status of the trial on the website, and report results. 
  • Requirements from Section 801 of the Food and Drug Administration Amendments Act:
    • Register the ACT on no later than 21 days after enrollment of the first participant.
    • Update the ACT on at least once every 12 months. Note that some items require update within 15 or 30 days of change (e.g. recruitment status, primary completion date).
    • Submit summary results (including adverse event information) no later than 1 year after the ACT’s primary completion Date.
  • To register your clinical trial:
  • Penalties for noncompliance include withholding of National Institutes of Health (NIH) grant funding and civil monetary penalties of up to $10,000 a day. Additionally, in order to consider the study for publication, the International Committee of Medical Journal Editors (ICJME) requires all clinical trials to be reported to the site prior to enrollment.
  • Questions regarding requirements can be submitted to Yolanda Griffin, manager of the Office of Clinical Trials Regulatory Affairs.