Guyton Research Lecture

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Joseph Loscalzo, MD, PhD

"Oxidative Enzymopathies and NO Insufficiency States in Cardiovascular Disease"
Wednesday, Feb. 28, 2007
University of Mississippi Medical Center, Room R153


Dr. Joseph Loscalzo is Hersey Professor of the Theory and Practice of Medicine at Harvard Medical School, Chairman of the Department of Medicine, and Physician-in-Chief at Brigham and Women's Hospital.

Dr. Loscalzo received his A.B. degree, summa cum laude, his PhD in biochemistry, and his MD from the University of Pennsylvania. His clinical training was completed at Brigham and Women's Hospital and Harvard Medical School, where he served as resident and chief resident in medicine and fellow in cardiovascular medicine.

After completing his training, Dr. Loscalzo joined the Harvard faculty and staff at Brigham and Women's Hospital in 1984. He rose to the rank of associate professor of medicine, chief of cardiology at the West Roxbury Veterans Administration Medical Center, and director of the Center for Research in Thrombolysis at Brigham and Women's Hospital. He joined the faculty of Boston University in 1994, first as chief of cardiology and, in 1997, Wade Professor and Chair of Medicine, Professor of Biochemistry, and director of the Whitaker Cardiovascular Institute. He returned to Harvard and Brigham and Women's Hospital in 2005. 

Dr. Loscalzo is recognized as an outstanding cardiovascular scientist and clinician. He has received many awards, including the Clinician-Scientist Award, the Distinguished Scientist Award, and the Research Achievement Award from the American Heart Association, the Research Career Development Award from the NIH, the George W. Thorn Award for Excellence in Teaching at Brigham and Women's Hospital, Educator of the Year Award in Clinical Medicine from Boston University, the Glaxo Cardiovascular Research Award, the Outstanding Investigator Prize from the International Society for Heart Research, and election to the American Society for Clinical Investigation, the Association of American Physicians, and the Institute of Medicine of the National Academies.

He has served on several NIH study sections and editorial boards, and has chaired the Gordon Conference on Thrombolysis. He served as an associate editor of the New England Journal of Medicine for nine years, chair of the Cardiovascular Board of the American Board of Internal Medicine, chair of the Research Committee of the American Heart Association, chair of the Scientific Board of the Stanley J. Sarnoff Society of Fellows for Research in the Cardiovascular Sciences, and chair of the Board of Scientific Counselors of the National Heart, Lung and Blood Institute of the National Institutes of Health. He is currently editor-in-chief of circulation, and was recently chosen as one of the senior editors of Harrison's Principles of Internal Medicine, replacing Dr. Eugene Braunwald. 

Dr. Loscalzo has been a visiting professor at many institutions and has authored or co-authored more than 500 scientific publications and authored or edited 23 books. He is also the recipient of many grants from the NIH and industry for his work in the areas of vascular biology, thrombosis and atherosclerosis over the past 20 years. He currently is principal investigator of four active NIH grants, including a Specialized Center of Research (SCOR) Grant in Ischemic Heart Disease from the NIH, now in its second cycle, and co-principal investigator of a newly awarded program project grant in oxidative stress in endothelial biology and disease.