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David Stec, PhD

Professor
Director, Transgenic Core                      
Office: G158
Lab: G154                                          
Transgenic Lab: G165
Office phone: (601) 815-1859
Lab phone:(601) 815-1366
E-mail: dstec@umc.edu

Areas of Expertise

  • General: Cardiovascular and renal physiology.
  • Specific: Mechanisms of hypertension; role of heme oxygenase and associated metabolites in the regulation of blood pressure and renal function; role of P450 metabolites of arachidonic acid in the regulation of blood pressure and renal function; role of heme oxygenase and associated metabolites in the regulation of body weight and metabolism.

Research Methods and Techniques

Genetically engineered mouse models; chronic instrumentation of mice for long-term blood pressure and renal function studies; chronic renal intramedullary interstitial infusion in mice; 24 hr measurement of metabolism including oxygen consumption, activity, heat production; antisense DNA targeting; molecular biology methods for study gene expression and activity.