General: Cardiovascular/renal physiology, biochemistry
Specific: Developmental programming of adult health and disease, low birth weight, intrauterine growth restriction, sex differences, hypertension
Our laboratory utilizes whole animal and molecular approaches including acute and chronic measurements of arterial pressure and renal hemodynamics (telemetry, GFR, ERPF, RVR), molecular, and biochemical assays (PCR, Western Blot, ELISA, etc).
Renal mechanisms of fetal programming of hypertension
Mechanisms by which sex hormones contribute to sex differences in hypertension programmed by developmental insult
Mismatch of prenatal and postnatal nutrition on later cardiovascular risk
Mechanisms responsible for increased sensitivity to renal injury in low birth weight