Recent publications

Study highlights potential breast cancer therapy 

Breast cancer research by Dr. Jawed A. Siddiqui, assistant professor in the Department of Cell and Molecular Biology and member of the Cancer Center and Research Institute, was published in the journal Biomed Pharmacotherapy. 

The study, “Alpha lipoic acid modulates metabolic reprogramming in breast cancer stem cells enriched 3D spheroids by targeting phosphoinositide 3-kinase: In silico and in vitro insights,” investigates the effects of alpha lipoic acid on the metabolic profile of breast cancer stem cells, which drive tumor resistance, progression, metastasis and recurrence. 

The research highlights the potential of alpha lipoic acid as a therapeutic agent for reprogramming cancer metabolism and enhancing chemotherapy efficacy.  

CCRI research focuses on key driver of ovarian cancer growth 

Research focusing on the MYB/AKT3 axis and ovarian cancer by Dr. Kunwar Somesh Vikramdeo and Dr. Shashi Anand, instructors in the Department of Cell and Molecular Biology; Dr. Seema Singh, professor of cell and molecular biology and CCRI associate director of education and training; Dr. Rod Rocconi, Ergon Chair for Cancer Research and CCRI director; and Dr. Ajay Singh, professor of cell and molecular biology and CCRI associate director of basic and translational research; was published in the Journal of Ovarian Research. 

“MYB/AKT3 axis is a key driver of ovarian cancer growth, aggressiveness, and chemoresistance” concluded that the MYB/AKT3 axis drives ovarian cancer growth, aggressiveness, and chemoresistance, highlighting its potential as a therapeutic target in ovarian cancer.