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Cancer Research Programs

Our research programs span the full continuum of cancer science—from uncovering fundamental tumor biology and immune interactions, to developing novel therapies, to advancing prevention and addressing unique health challenges in the region. Together, these programs drive innovation from the lab to the clinic and into the community, with the shared goal of improving outcomes for all patients. 

Cancer Biology and Immunology – Understanding tumor mechanisms and immune interactions 

This program investigates the molecular and cellular mechanisms underlying cancer initiation, progression and metastasis, with a particular emphasis on the tumor microenvironment and tumor-immune interactions. Leveraging advanced technologies, we aim to uncover key insights into how cancer cells circumvent normal regulatory processes, evade immune responses, and develop resistance to treatment.  These insights into tumor biology and immune evasion lay the groundwork for drug discovery and the development of targeted, mechanism-based therapies aimed at overcoming treatment resistance and improving patient outcomes. 

Experimental Therapeutics – From lab to clinic: drug development and early-phase trials 

The program integrates cutting-edge approaches in molecular biology, pharmacology and bioinformatics to discover new drug targets and optimize drug design. Researchers in this program use high-throughput screening, structure-based drug design, nanotechnology and advanced modeling techniques to identify promising compounds and evaluate their efficacy, safety and potential for clinical use. Additionally, the program investigates innovative therapeutic strategies, including targeted therapies and combination therapies, to improve treatment outcomes. Translation of discoveries from the lab to the clinic is accelerated through collaboration with clinical researchers, ensuring that novel therapies address unmet medical needs and enhance patient care.  

Population Health and Cancer Control – Addressing disparities, prevention, and community outreach 

The program aims to reduce the burden of cancer through early detection, prevention, and health promotion strategies. It combines epidemiological research, behavioral science and public health strategies to identify cancer risk factors and guide the development of effective interventions. Researchers examine lifestyle factors, environmental exposures, genetic predispositions and socio-economic determinants that contribute to cancer risk and patient outcomes. By finding patterns of cancer incidence and survivorship at the population level, the goal of the program is to implement evidence-based preventive measures, including screening guidelines, vaccination programs and health education initiatives. The ultimate objective is to reduce cancer incidence, improve early detection and promote healthier lifestyles to lower cancer-related morbidity and mortality across communities.