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Lorena M. Amaral, PharmD , PhD

Office: Guyton Building, G454
Lab: (601) 815-1402
Office: (601) 815-1401

Research interest

  • Women's health
  • Hypertension in pregnancy and preeclampsia

Current research

My research interest is to expand our clinical studies and knowledge regarding the pathophysiology of preeclampsia and to use our clinical and basic studies to discover novel therapeutic targets for this for this hypertensive disorder of pregnancy.

Importantly, a large percentage of our patient population at UMMC Wiser hospital have preeclampsia associated with significantly lower circulating progesterone compared to non-hypertensive normal pregnant women. My current work is focused on two main projects. The goal of our first project is to examine the effects of 17-OHPC on the immunologic mechanisms related to preeclampsia and secondly to test the effect of PIBF, Progesterone induced blocking factor, either by supplementation or stimulation via 17-hydroxyprogesterone caproate (17-OHPC) in rodent models of preeclampsia.

My career goal is to achieve a position as an independent researcher in an academic setting in physiology/pharmacology science to allow translational studies into mechanisms and potential novel therapies for preeclampsia.