2023 Publications

• Solise D, Campbell N, Ashraf U, Herrock O, Crudup B, Mallette J, Willis A, Rawls AZ, Turner T, Cockrell K, Zheng B, Deer E, Amaral L, Alexander BT, Lamarca B. Inhibition of angiotensin II type 1 receptor agonistic autoantibodies by direct binding does not impact reduced uterine perfusion pressure offspring birthweight and blood pressure at adulthood. Am J Obstet Gynecol MFM. 2023 Jun;5(6):100945. doi: 10.1016/j.ajogmf.2023.100945. Epub 2023 Mar 27.
• Badmus OO, Kipp ZA, Bates EA, da Silva AA, Taylor LC, Martinez GJ, Lee WH, Creeden JF, Hinds TD Jr, Stec DE. The loss of hepatic PPARα in mice causes hypertension and cardiovascular disease. Am J Physiol Regul Integr Comp Physiol. 2023 May 22. doi: 10.1152/ajpregu.00057.2023. Online ahead of print.
• Speed JS, Pollock DM, Clemmer JS. Don't sweat the small stuff: skin mechanisms of sodium homeostasis and associations with long-term blood pressure.Clin Sci (Lond). 2023 May 18;137(9):769-772. doi: 10.1042/CS20230163.
• Badmus OO, Hinds TD Jr, Stec DE. Mechanisms Linking Metabolic-Associated Fatty Liver Disease (MAFLD) to Cardiovascular Disease. Curr Hypertens Rep. 2023 May 16. doi: 10.1007/s11906-023-01242-8. Online ahead of print.
• Huffman AM, Syed M, Rezq S, Anderson CD, Yanes Cardozo LL, Romero DG.  Loss of microRNA-21 protects against acetaminophen-induced hepatotoxicity in mice. Arch Toxicol.2023 May 14. doi: 10.1007/s00204-023-03499-z. Online ahead of print.
• Alexander BT, South AM, August P, Bertagnolli M, Ferranti EP, Grobe JL, Jones EJ, Loria AS, Safdar B, Sequeira-Lopez MLS; American Heart Association Council on the Kidney in Cardiovascular Disease; Council on Cardiovascular and Stroke Nursing; Council on Cardiovascular Radiology and Intervention; Council on Hypertension; and Council on Lifestyle and Cardiometabolic Health. Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American Heart Association. Hypertension.2023 May;80(5):e75-e89. doi: 10.1161/HYP.0000000000000227. Epub 2023 Mar 23.
• Vitek L, Hinds TD Jr, Stec DE, Tiribelli C. The physiology of bilirubin: health and disease equilibrium. Trends Mol Med. 2023 Apr;29(4):315-328. doi: 10.1016/j.molmed.2023.01.007. Epub 2023 Feb 22.
• Clemmer JS, Hillegass WB, Taylor EB. Antihypertensive effects of immunosuppressive therapy in autoimmune disease.  J Hum Hypertens.2023 Apr;37(4):300-306. doi: 10.1038/s41371-022-00682-0. Epub 2022 Apr 8.
• Clemmer JS, Ward TJ, Lirette ST. Retrospective analysis of SGLT2 inhibitors in heart failure with preserved ejection fraction. ESC Heart Fail. 2023 Apr 11. doi: 10.1002/ehf2.14347. Online ahead of print.
• Mallette JH, Crudup BF, Alexander BT. Growth Restriction in Preeclampsia: Lessons from Animal Models. CurrOpin Physiol. 2023 Apr;32:100647. doi: 10.1016/j.cophys.2023.100647. Epub 2023 Feb 13.
• Chen JX, Li L, Cantrell AC, Williams QA, Zeng H.  High Glucose Activates Prolyl Hydroxylases and Disrupts HIF-α Signaling via the P53/TIGAR Pathway in Cardiomyocyte. Cells. 2023 Mar 31;12(7):1060. doi: 10.3390/cells12071060.
• Hamid A, Yimer WK, Oshunbade AA, Kamimura D, Clark D 3rd, Fox ER, Min YI, Muntner P, Shimbo D, Pandey A, Shah AM, Mentz RJ, Jones DW, Bertoni AG, Hall JE, Correa A, Butler J, Hall ME. Impact of Diabetes and Hypertension on Left Ventricular Structure and Function: The Jackson Heart Study. J Am Heart Assoc. 2023 Mar 21;12(6):e026463. doi: 10.1161/JAHA.122.026463. Epub 2023 Mar 7.
• Fang X, Tang C, Zhang H, Border JJ, Liu Y, Shin SM, Yu H, Roman RJ, Fan F. Longitudinal characterization of cerebral hemodynamics in the TgF344-AD rat model of Alzheimer's disease. Geroscience. 2023 Mar 18. doi: 10.1007/s11357-023-00773-x. Online ahead of print.
• Ekperikpe US, Poudel B, Shields CA, Mandal S, Cornelius DC, Williams JM. Neutralizing MIP3 α Reduces Renal Immune Cell Infiltration and Progressive Renal Injury in Young Obese Dahl Salt-Sensitive Rats. J PharmacolExp Ther. 2023 Mar;384(3):445-454. doi: 10.1124/jpet.122.001298. Epub 2022 Dec 5.PMID: 36507846.
• Barnes CC, Yee KT, Vetter DE. Conditional Ablation of Glucocorticoid and Mineralocorticoid Receptors from Cochlear Supporting Cells Reveals Their Differential Roles for Hearing Sensitivity and Dynamics of Recovery from Noise-Induced Hearing Loss. Int J Mol Sci. 2023 Feb 7;24(4):3320. doi: 10.3390/ijms24043320.
• Kipp ZA, Martinez GJ, Bates EA, Maharramov AB, Flight RM, Moseley HNB, Morris AJ, Stec DE, Hinds TD Jr. Bilirubin Nanoparticle Treatment in Obese Mice Inhibits Hepatic Ceramide Production and Remodels Liver Fat Content. Metabolites. 2023 Feb 1;13(2):215. doi: 10.3390/metabo13020215.
• Bates EA, Kipp ZA, Martinez GJ, Badmus OO, Soundarapandian MM, Foster D, Xu M, Creeden JF, Greer JR, Morris AJ, Stec DE, Hinds TD Jr. Suppressing Hepatic UGT1A1 Increases Plasma Bilirubin, Lowers Plasma Urobilin, Reorganizes Kinase Signaling Pathways and Lipid Species and Improves Fatty Liver Disease. Biomolecules. 2023 Jan 29;13(2):252. doi: 10.3390/biom13020252.
• Flack KD, Vítek L, Fry CS, Stec DE, Hinds TD Jr. Cutting edge concepts: Does bilirubin enhance exercise performance? Front Sports Act Living. 2023 Jan 11;4:1040687. doi: 10.3389/fspor.2022.1040687. eCollection 2022.
• Martin BE, Taylor EB, Attipoe EM, Wu W, Stec DE, Showmaker KC, Garrett MR. Sex and Molecular Differences in Cardiovascular Parameters at Peak Influenza Disease in Mice. Physiol Genomics.2023 Jan 16. doi: 10.1152/physiolgenomics.00146.2022. Online ahead of print.
• Rivera-Gonzalez O, Case CT, Wilson NA, Speed JS, Taylor EB. Endothelin receptor antagonism improves glucose tolerance and adipose tissue inflammation in an experimental model of systemic lupus erythematosus.  Am J Physiol Endocrinol Metab. 2023 Jan 1;324(1):E73-E84. doi: 10.1152/ajpendo.00274.2022. Epub 2022 Dec 7.