Junie "J Paula" P. Warrington Tate, PhD
Associate Professor
Department:
SOM-Neurology
Email:
jpwarrington@umc.edu
Work Phone:
(601) 815-8969
Biography
Junie PAULA Warrington, PhD is an associate professor in the department of Neurology.
She received a PhD in neuroscience from the University of Oklahoma Health Sciences Center in 2011 and has co-authored over 30 peer-reviewed manuscripts, 1 commentary, 2 editorial, and 1 book chapter. Dr. Warrington’s research has been continuously funded by a Pre- and Post-doctoral fellowship from the American Heart Association, a K99/R00 Pathway to Independence grant, along with an administrative supplement and NIH R56 grant from the National Institutes of Health.
Dr. Warrington is co-Editor-in-Chief of the Journal of Neuroscience Research, consulting editor of AJP: Heart, and served as social media editor of Stroke.
Using translational preclinical animal models, Dr. Warrington works on identifying pathophysiological mechanisms contributing to neurovascular abnormalities and seizures in preeclampsia-complicated pregnancies during antepartum, peripartum, and postpartum periods.
Education
| University of Mississippi Medical Center, Postdoctoral Fellowship, Physiology & Biophysics | 2013 |
| University of Oklahoma Health Sciences Center, PhD, Neuroscience/ Behavioral Neuroscience | 2011 |
| Fort Valley State University, BA, Psychology | 2007 |
Current Positions
| Associate Director, School of Graduate School in the Health Sciences | 08/2022 - Present |
| Associate Professor, School of Medicine, Department of Neurology | 07/2022 - Present |
| The University of Mississippi Medical Center Jackson, Mississippi 39216 | |
Academic Appointments or Other Previous Appointments
| Assistant Professor, School of Medicine, Department of Neurobiology and Anatomical Sciences | 07/2017 - 06/2022 |
| Assistant Professor, University of Mississippi Medical Center, School of Medicine, Department of Neurology | 05/2017 - 06/2022 |
| Instructor, University of Mississippi Medical Center, School of Medicine, Department of Physiology And Biophysics | 07/2013 - 04/2017 |
| Assistant Professor, University of Mississippi Medical Center, School of Graduate School in the Health Sciences, Department of Neurobiology and Anatomical Sciences |
Sponsored Program Funding
| Intramural, EEG Patterns in Pregnancy: Eclampsia vs. Epilepsy, MCCTR Pilot Grant | 12/2023 - 11/2024 |
| Extramural, Role of Endocannabinoid System in Seizure Sensitivity in Eclampsia, NIH NINDS | 07/2022 - 06/2023 |
| Extramural, Mechanisms of Seizure in Pregnancy and Preeclampsia, NIH NHLBI | 09/2021 - 08/2023 |
| Extramural, Porter Physiology Development Fellowship, American Physiological Society | 09/2021 - 06/2022 |
| Extramural, Mechanisms of Seizure in Pregnancy and Preeclampsia, NIH/NHLBI | 07/2021 - 06/2026 |
| Extramural, Preeclampsia and Offspring Neurovascular and Cognitive Dysfunction, NHLBI/UCSD | 02/2021 - 01/2021 |
| Extramural, Cerebrovascular Abnormalities in Preeclampsia, NHLBI | 09/2019 - 04/2021 |
| Extramural, NIH R00 Grant, NIH NHLBI | 05/2017 - 04/2021 |
| Extramural, NIH K99 Award, NIH NHLBI | 05/2016 - 04/2017 |
| Intramural, COBRE Pilot Grant | 01/2015 - 04/2017 |
| Extramural, Postdoctoral Fellowship, AHA | 07/2013 - 06/2015 |
| Extramural, Predoctoral Fellowship, AHA | 07/2009 - 06/2011 |
Publications
Journal Article | |
| Kaur S, Darden CJ, Adegbola GM, Warrington JP, History of hypertensive disorders of pregnancy and risk of Alzheimer's disease and vascular dementia. Frontiers in neuroendocrinology, 2025 May 12;78:101198 | 2025 |
| Smith AM, Ray TJ, Hulitt AA, Vita SM, Warrington JP, Santos CDSE, Grayson BE, High-fat diet consumption negatively influences closed-head traumatic brain injury in a pediatric rodent model. Experimental neurology, 2024 Sep;379:114888 | 2024 |
| Warrington JP, Collins HE, Davidge ST, do Carmo JM, Goulopoulou S, Intapad S, Loria AS, Sones JL, Wold LE, Zinkhan EK, Alexander BT, Guidelines for in vivo models of developmental programming of cardiovascular disease risk. American journal of physiology. Heart and circulatory physiology, 2024 Jul 1;327(1):H221-H241 | 2024 |
| Collins HE, Alexander BT, Care AS, Davenport MH, Davidge ST, Eghbali M, Giussani DA, Hoes MF, Julian CG, LaVoie HA, Olfert IM, Ozanne SE, Bytautiene Prewit E, Warrington JP, Zhang L, Goulopoulou S, Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum. American journal of physiology. Heart and circulatory physiology, 2024 Jul 1;327(1):H191-H220 | 2024 |
| Kaur S, Ewing HT, Warrington JP, Blood-Brain Barrier Dysfunction in Hypertensive Disorders of Pregnancy. Current hypertension reports, 2023 Dec;25(12):463-470 | 2023 |
| Jones-Muhammad M, Pryor T, Shao Q, Freeman KB, Warrington JP, Increased hippocampal cannabinoid 1 receptor expression is associated with protection from severe seizures in pregnant mice with reduced uterine perfusion pressure. Journal of neuroscience research, 2023 Dec;101(12):1884-1899 | 2023 |
| Robinson AT, Jenkins NDM, Sanchez SO, Haack KKV, Lee DL, Mathis KW, Warrington JP, Supporting and promoting Black physiologists: how can the APS help? American journal of physiology. Heart and circulatory physiology, 2023 Jun 1;324(6):H782-H785 | 2023 |
| Warrington JP, Jones-Muhammad M, Thompson RO, Pryor T, Shao Q, Gunturu M, Retinal Venule Coverage by Pericytes Decreases in Multiparous Mice in a Time-Dependent Manner Post-Delivery. International journal of molecular sciences, 2023 Feb 16;24(4) | 2023 |
| Jones-Muhammad M, Shao Q, Warrington JP Increased seizure sensitivity in pregnant mice with genetic knockdown of acid sensing ion channel 2a is associated with impaired hippocampal inflammatory response Frontiers in Physiology. 2022 | 2022 |
| Warrington JP, Shao Q, Clayton AM, Maeda KJ, Beckett AG, Garrett MR, Sasser JM, Pial Vessel-Associated Microglia/Macrophages Increase in Female Dahl-SS/Jr Rats Independent of Pregnancy History. International journal of molecular sciences, 2022 Mar 21;23(6) | 2022 |
| Maeda KJ, McClung DM, Showmaker KC, Warrington JP, Ryan MJ, Garrett MR, Sasser JM, Endothelial cell disruption drives increased blood-brain barrier permeability and cerebral edema in the Dahl SS/jr rat model of superimposed preeclampsia. American journal of physiology. Heart and circulatory physiology, 2021 Feb 1;320(2):H535-H548 | 2021 |
| Warrington JP, Lessons learned on my journey to a career as a minority woman in Neuroscience. Journal of neuroscience research, 2021 Jan;99(1):24-25 | 2021 |
| Jones-Muhammad M, Shao Q, Cain-Shields L, Shaffery JP, Warrington JP, Acid Sensing Ion Channel 2a Is Reduced in the Reduced Uterine Perfusion Pressure Mouse Model and Increases Seizure Susceptibility in Pregnant Mice. Cells, 2021 May 8;10(5) | 2021 |
| Jones-Muhammad M, Warrington JP, Cerebral Blood Flow Regulation in Pregnancy, Hypertension, and Hypertensive Disorders of Pregnancy. Brain sciences, 2019 Sep 4;9(9) | 2019 |
| Giambrone AB, Logue OC, Shao Q, Bidwell GL 3rd, Warrington JP, Perinatal Micro-Bleeds and Neuroinflammation in E19 Rat Fetuses Exposed to Utero-Placental Ischemia. International journal of molecular sciences, 2019 Aug 20;20(16) | 2019 |
| Warrington JP, Fan F, Duncan J, Cunningham MW, LaMarca BB, Dechend R, Wallukat G, Roman RJ, Drummond HA, Granger JP, Ryan MJ, The angiotensin II type I receptor contributes to impaired cerebral blood flow autoregulation caused by placental ischemia in pregnant rats. Biology of sex differences, 2019 Dec 11;10(1):58 | 2019 |
| Giambrone AB, Warrington JP, The rat model of placental ischemia as a model of postpartum posterior cortical atrophy? Neural regeneration research, 2018 Dec;13(12):2094-2095 | 2018 |
| Clayton AM, Shao Q, Paauw ND, Giambrone AB, Granger JP, Warrington JP, Postpartum increases in cerebral edema and inflammation in response to placental ischemia during pregnancy. Brain, behavior, and immunity, 2018 May;70:376-389 | 2018 |
| Bakrania B, Duncan J, Warrington JP, Granger JP, The Endothelin Type A Receptor as a Potential Therapeutic Target in Preeclampsia. International journal of molecular sciences, 2017 Feb 28;18(3) | 2017 |
| Warrington JP, Drummond HA, Granger JP, Ryan MJ, Placental ischemia-induced increases in brain water content and cerebrovascular permeability: role of TNF-α. American journal of physiology. Regulatory, integrative and comparative physiology, 2015 Dec 1;309(11):R1425-31 | 2015 |
| Warrington JP, Placental ischemia increases seizure susceptibility and cerebrospinal fluid cytokines. Physiological reports, 2015 Nov;3(11) | 2015 |
| Warrington JP, Coleman K, Skaggs C, Hosick PA, George EM, Stec DE, Ryan MJ, Granger JP, Drummond HA, Heme oxygenase-1 promotes migration and β-epithelial Na+ channel expression in cytotrophoblasts and ischemic placentas. American journal of physiology. Regulatory, integrative and comparative physiology, 2014 May;306(9):R641-6 | 2014 |
| Tucsek Z, Toth P, Tarantini S, Sosnowska D, Gautam T, Warrington JP, Giles CB, Wren JD, Koller A, Ballabh P, Sonntag WE, Ungvari Z, Csiszar A, Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice. The journals of gerontology. Series A, Biological sciences and medical sciences, 2014 Nov;69(11):1339-52 | 2014 |
| George EM, Warrington JP, Spradley FT, Palei AC, Granger JP, The heme oxygenases: important regulators of pregnancy and preeclampsia. American journal of physiology. Regulatory, integrative and comparative physiology, 2014 Oct 1;307(7):R769-77 | 2014 |
| Ashpole NM, Warrington JP, Mitschelen MC, Yan H, Sosnowska D, Gautam T, Farley JA, Csiszar A, Ungvari Z, Sonntag WE, Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells. American journal of physiology. Heart and circulatory physiology, 2014 Sep 15;307(6):H858-68 | 2014 |
| Yan H, Mitschelen M, Toth P, Ashpole NM, Farley JA, Hodges EL, Warrington JP, Han S, Fung KM, Csiszar A, Ungvari Z, Sonntag WE, Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat. The journals of gerontology. Series A, Biological sciences and medical sciences, 2014 Nov;69(11):1353-62 | 2014 |
| Warrington JP, Fan F, Murphy SR, Roman RJ, Drummond HA, Granger JP, Ryan MJ, Placental ischemia in pregnant rats impairs cerebral blood flow autoregulation and increases blood-brain barrier permeability. Physiological reports, 2014 Aug 1;2(8) | 2014 |
| Intapad S, Warrington JP, Spradley FT, Palei AC, Drummond HA, Ryan MJ, Granger JP, Alexander BT, Reduced uterine perfusion pressure induces hypertension in the pregnant mouse. American journal of physiology. Regulatory, integrative and comparative physiology, 2014 Dec 1;307(11):R1353-7 | 2014 |
| Palei AC, Spradley FT, Warrington JP, George EM, Granger JP, Pathophysiology of hypertension in pre-eclampsia: a lesson in integrative physiology. Acta physiologica (Oxford, England), 2013 Jul;208(3):224-33 | 2013 |
| Warrington JP, George EM, Palei AC, Spradley FT, Granger JP, Recent advances in the understanding of the pathophysiology of preeclampsia. Hypertension (Dallas, Tex. : 1979), 2013 Oct;62(4):666-73 | 2013 |
| Haase N, Herse F, Spallek B, Haase H, Morano I, Qadri F, Szijártó IA, Rohm I, Yilmaz A, Warrington JP, Ryan MJ, Gollasch M, Müller DN, Dechend R, Wallukat G, Amyloid-β peptides activate α1-adrenergic cardiovascular receptors. Hypertension (Dallas, Tex. : 1979), 2013 Nov;62(5):966-72 | 2013 |
| Valcarcel-Ares MN, Gautam T, Warrington JP, Bailey-Downs L, Sosnowska D, de Cabo R, Losonczy G, Sonntag WE, Ungvari Z, Csiszar A, Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging. The journals of gerontology. Series A, Biological sciences and medical sciences, 2012 Aug;67(8):821-9 | 2012 |
| Lee WH, Warrington JP, Sonntag WE, Lee YW, Irradiation alters MMP-2/TIMP-2 system and collagen type IV degradation in brain. International journal of radiation oncology, biology, physics, 2012 Apr 1;82(5):1559-66 | 2012 |
| VanGuilder Starkey HD, Van Kirk CA, Bixler GV, Imperio CG, Kale VP, Serfass JM, Farley JA, Yan H, Warrington JP, Han S, Mitschelen M, Sonntag WE, Freeman WM, Neuroglial expression of the MHCI pathway and PirB receptor is upregulated in the hippocampus with advanced aging. Journal of molecular neuroscience : MN, 2012 Sep;48(1):111-26 | 2012 |
| Warrington JP, Csiszar A, Johnson DA, Herman TS, Ahmad S, Lee YW, Sonntag WE, Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice. American journal of physiology. Heart and circulatory physiology, 2011 Mar;300(3):H736-44 | 2011 |
| Mitschelen M, Yan H, Farley JA, Warrington JP, Han S, Hereñú CB, Csiszar A, Ungvari Z, Bailey-Downs LC, Bass CE, Sonntag WE, Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression. Neuroscience, 2011 Jun 30;185:50-60 | 2011 |
| VanGuilder HD, Bixler GV, Brucklacher RM, Farley JA, Yan H, Warrington JP, Sonntag WE, Freeman WM, Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment. Journal of neuroinflammation, 2011 Oct 11;8:138 | 2011 |
| Mitschelen M, Garteiser P, Carnes BA, Farley JA, Doblas S, Demoe JH, Warrington JP, Yan H, Nicolle MM, Towner R, Sonntag WE, Basal and hypercapnia-altered cerebrovascular perfusion predict mild cognitive impairment in aging rodents. Neuroscience, 2009 Dec 15;164(3):918-28 | 2009 |
| Warrington JP, Csiszar A, Mitschelen M, Lee YW, Sonntag WE, Whole brain radiation-induced impairments in learning and memory are time-sensitive and reversible by systemic hypoxia. PloS one, 2012;7(1):e30444 | |
| Warrington JP, Ashpole N, Csiszar A, Lee YW, Ungvari Z, Sonntag WE, Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications. Journal of vascular research, 2013;50(6):445-57 | |
| Zhang LW, Warrington JP, Magnesium Sulfate Prevents Placental Ischemia-Induced Increases in Brain Water Content and Cerebrospinal Fluid Cytokines in Pregnant Rats. Frontiers in neuroscience, 2016;10:561 | |
| Beckett AG, McFadden MD, Warrington JP, Preeclampsia history and postpartum risk of cerebrovascular disease and cognitive impairment: Potential mechanisms. Frontiers in physiology, 2023;14:1141002 | |
| Jones-Muhammad M, Shao Q, Warrington JP, Increased seizure sensitivity in pregnant mice with genetic knockdown of acid sensing ion channel 2a is associated with impaired hippocampal inflammatory response. Frontiers in physiology, 2022;13:983506 | |
Abstracts | |
| Duncan JW, Warrington JP, Ryan MJ, Granger JP, Drummond HA TNFα and IL-17 downregulates βENaC expression and reduces migration in vascular smooth muscle cells FASEB J April 2017 31:851.2 | |
| Warrington JP, Granger JP, Ryan MJ, Drummond HA Reductions in βENaC and ASIC2 Induce Preeclampsia-Like Symptoms in Pregnant Mice FASEB J April 2016 30:1214.9 | |
| Palei AC, Warrington JP, Granger JP The Effect of Placental Ischemia-Induced Hypertension on Circulating Copeptin Levels of Pregnant Rats FASEB J April 2016 30:lb765 | |
| Warrington JP, Ryan MJ, Drummond HA, Spradley FT, Granger JP Tumor Necrosis Factor induces cerebral edema and increased cerebrovascular permeability in normal pregnant rats FASEB J April 2013 27:907.9 | |
| Warrington JP, Csiszar A, Mitschelen M, Yan H, Han S, Sosnowska D, Gautam T, Farley JA, Lee YW, Ungvari Z, Sonntag WE Bone marrow cells are necessary for cerebral microvascular recovery following whole brain radiation therapy in mice FASEB J April 2012 26:682.6 | |
| Ungvari Z, Valcarcel-Ares MN, Gautam T, Warrington JP, Bailey-Downs LC, Sosnowska D, de Cabo R, Sonntag WE, Csiszar A Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging FASEB J April 2012 26:682.10 | |
| Warrington JP, Fan F, Murphy S, Roman R, Drummond H, Granger J, Ryan M Placental Ischemia Impairs Cerebral Blood Flow Autoregulation and Increases Blood-Brain Barrier Permeability in Pregnant Rats FASEB J April 2015 29:646.7 | |
| Warrington JP Pentylenetetrazol-Induced Seizures during Placental Ischemia: A Potential Model of Eclampsia? FASEB J April 2015 29:837.5 | |
| Warrington JP, Csiszar A, Johnson DA, Herman TS, Ahmad S, Lee YW, Sonntag WE Systemic hypoxia reverses whole brain radiation-induced microvascular rarefaction FASEB J April 2011 25:636.15 | |
| Intapad S, Warrington J, Spradley F, Palei A, Drummond H, Ryan M, Granger J, Alexander B A reduction in uterine perfusion pressure induces hypertension during pregnancy in the mouse FASEB J April 2014 28:1084.5 | |
| Warrington J, Drummond H, Ryan M, Granger J The role of TNF alpha in placental ischemia-induced cerebrovascular abnormalities FASEB J April 2014 28:1084.6 | |
| Warrington JP, Fan F, LaMarca BB, Dechend R, Wallukat G, Roman RJ, Drummond HA, Granger JP, Ryan MJ Agonistic Autoantibodies to Angiotensin II Type I Receptor Contributes Partly to Placental Ischemia-induced Cerebrovascular Abnormalities Hypertension. 2015;66:A127 | |
| Warrington JP, George EM, Stec DE, Ryan MJ, Granger JP, Drummond HA HO-1 Induction Increases ßENaC in Ischemic Placentas and Cultured Cytotrophoblasts Hypertension. 2013;62:A281 | |
| Warrington JP, George EM, Ryan MJ, Drummond HA, Granger JP Hemeoxygenase-1 Induction Restores Beta ENaC Expression in Ischemic Placentas Hypertension. 2012;60:A209 | |
| Haase N, Herse F, Spallek B, Haase H, Wallukat G,Qadri F, Szijártó IA, Rohm I, Yilmaz A, Warrington JP, Gollasch M, Ryan MJ, Müller DN, Dechend R Vasoactivity of the Alzheimer ß-Amyloid Peptides is Mediated by an Activation of the a1-Adrenoreceptor Hypertension. 2013;62:A459 | |
| Warrington JP Placental Ischemia Increases Seizure Susceptibility in Pregnant Rats Stroke. 2015;46:AWP389 | |
| Jones-Muhammad MA, Thompson R, Shao Q, Warrington JP Impact of placental ischemia on hippocampal ASIC2a and glutamate receptor protein expression in mice Hypertension, 2019 | |
| Clayton AM, Shao Q, Maeda KJ, Garrett MR, Sasser JM, Warrington JP Postpartum changes in microglia in a rat model of superimposed preeclampsia FASEB, 2019 | |
| Giambrone AB, Logue OC, Shao Q, Bidwell GL, Warrington JP Placental ischemia exposure leads to increased cerebral microbleeds in embryonic day 19 rat offspring Stroke, 2019 | |
| Maeda KJ, McClung DM, Warrington JP, Garrett MR, Ryan MJ, Sasser JM Cerebrovascular Dysfunction in the Dahl S Rat Model of Superimposed Preeclampsia | |
| Warrington JP, Logue OC, Bidwell GL, Shao Q Placental Ischemia Exposure leads to a Pro-Inflammatory Environment in Brains of Embryonic Day 19 Rat Offspring Hypertension, 2018 | |
| Giambrone AB, Shao Q, Warrington JP Placental Ischemia Leads to Regional Astrocyte Activation: Role of TNFα FASEB, 2018 | |
| Clayton AM. Shao Q, Paauw ND, Granger JP, Warrington JP Placental Ischemia leads to Postpartum Cerebral Inflammation and Edema in Rats FASEB, 2018 | |
| Duncan JW, Warrington JP, Drummond HA., Granger JP, Ryan MJ TNFα Impairs Cerebral Blood Flow (CBF) Autoregulation in Pregnant Rats FASEB, 2018 | |
| Warrington JP, Duncan J, Drummond HA, Granger JP, Ryan MJ Interleukin-17 infusion promotes cerebral edema and increased blood-brain barrier permeability in pregnant rats Hypertension, 2017 | |
| Thompson R, Shao Q, Warrington JP Impact of multi-parity on retinal vascular structure in middle-aged mice Stroke, 2020 | |
| Vig P, Ryu J, Lee H, Warrington J, Janorkar A, Pal P, Lopez M Optimizing E x Vivo Model of Traumatic Brain Injury to Test Biomolecules of Therapeutic Interest FASEB Journal, 2020 | |
| Duncan J, Warrington J, Nemeth Z, Granger J, Drummond H, Ryan M Interleukin‐17 Impairs Cerebrovascular Function, Increases Blood‐Brain‐Barrier Permeability, and Induces Cerebral Edema in Pregnant Rats FASEB Journal, 2020 | |
| Sherrod AM*, Shao Q, Thompson R, Griffin AD, Jones-Muhammad M*, Warrington JP Impact of reduced ASIC2 on cortical thickness, microglia density, and brain water content in E18.5 mouse fetuses FASEB Journal, 2020 | |
| Jones-Muhammad MA*, Thompson R, Shao Q, Warrington JP Impact of reduced ASIC2 and pregnancy on seizure susceptibility in mice FASEB Journal, 2020 | |
| Warrington JP, Shao Q, Clayton AM*, Maeda KJ, Garrett MR, Sasser JM Chronic Hypertension Increases Pial Perivascular Microglia in Female Dahl-S Rats FASEB Journal, 2020 | |
| Beckett AG*, Clayton AM*, Shao Q, Maeda KJ, Garrett MR, Sasser JM, Warrington JP Prenatal Sildenafil treatment prevents postpartum neuroinflammation in the Dahl-SS/Jr model of superimposed preeclampsia FASEB Journal, 2021 | |
| Jones-Muhammad MA*, Shao Q, Warrington JP Placental Ischemia increases Seizure Susceptibility through Reduced ASIC2a Expression FASEB Journal, 2021 | |
| Maeda KJ, Warrington JP, Duncan J, Granger JP, Garrett MR, Ryan MJ, Sasser JM Cerebral Edema and Blood Brain Barrier Dysfunction in the Dahl S Rat Model of Superimposed Preeclampsia FASEB J April 2017 31:lb857 | |
| Warrington JP, Spradley FT, Chade AR, Ryan MJ, Granger JP, Drummond HA βENaC is Required for Placental Vascular Remodeling in Mice FASEB J April 2017 31:1034.1 | |
Book Chapter | |
| Spradley FT, George EM, Palei AC, Warrington JP, Granger JP Preeclampsia: Angiogenic factors, blood pressure, and the kidney. Chronic Kidney Disease and Hypertension, Springer New York Copyright 2015 | |
Editorial Commentary | |
| Jones-Muhammad M, Warrington JP Redefining the Cerebral Autoregulatory Range of Blood Pressures: Not as Wide as Previously Reported Physiological Reports, In Press, 2021 | |
Electronic Publications | |
| Maternal Vaping Impairs Vascular Function in the Offspring https://ajpheart.podbean.com/e/maternal-vaping-impairs-vascular-function-in-the-offspring/ | 2021 |
| Microvascular Function following Preeclampsia. American Journal of Physiology: Heart and Circulatory Physiology Podcast, 2021 | 2021 |
| Development of the NRF2 knockout rat American Journal of Physiology: Heart and Circulatory Physiology Podcast | 2016 |
| Ghiani CA, Warrington JP NIH Sex as a Biological Variable Primer Supplement | |
Editorial | |
| Jones-Muhammad M, Warrington JP, When high-fat diet plus hypertension does not equal vascular dysfunction. American journal of physiology. Heart and circulatory physiology, 2021 Jul 1;321(1):H128-H130 | 2021 |
| Jones-Muhammad M, Warrington JP, Redefining the cerebral autoregulatory range of blood pressures: Not as wide as previously reported. Physiological reports, 2021 Sep;9(17):e15006 | 2021 |
Presentations
| National and International Invited Seminars/Lectures, Postpartum Neurovascular and Cognitive Changes in rodents following Seizures and Hypertensive Pregnancy Disorders, Zooming in Preeclampsia Seminar Series, Zoom | 04/2024 |
| Platform Presentations, Pathophysiological mechanisms contributing to neurovascular abnormalities in hypertensive pregnancy disorders, Advancing the Study of Stroke in Women/PROWESS, Arlington Virginia | 04/2024 |
| National and International Invited Seminars/Lectures, Hypertensive Disorders of Pregnancy and Late-Life Vascular Dementia: Clinical and Translational Evidence and Mechanisms, Dartmouth Health | 02/2024 |
| National and International Invited Seminars/Lectures, Unravelling Cerebrovascular and Retinal Vascular-Associated changes following pregnancy, University of South Carolina School of Medicine CTCR | 02/2024 |
| Invited Symposia, When the bun is out of the oven: Neurovascular and Cognitive changes in offspring exposed to preeclampsia-like conditions, American Physiological Summit, Long Beach, CA | 04/2023 |
| National and International Invited Seminars/Lectures, Mechanisms of Seizures in Pregnancy, Zooming in Preeclampsia Seminar Series, WebEx | 04/2023 |
| Regional Invited Seminars/Lectures, Neurovascular and Cognitive Effects of Exposure to Reduced Uterine Perfusion, University of Alabama at Birmingham | 03/2023 |
| National and International Invited Seminars/Lectures, Neurovascular and Cognitive Dysfunction in Postpartum Dams, Women’s Cardiovascular and Brain Health (WCBH) Symposium, University of North Texas Health Science Center | 02/2023 |
| National and International Invited Seminars/Lectures, From Mom to Offspring: Neurovascular and Cognitive Physiology after Complicated Pregnancy, Tulane University Brain Institute | 01/2023 |
| National and International Invited Seminars/Lectures, Cerebrovascular and Cognitive Changes in Adult Mouse Offspring exposed to Reduced Uterine Perfusion Pressure during Pregnancy, GRIVAS 2022, Hybrid | 08/2022 |
| Invited Symposia, Career Advancement: Hurdles and Successes, American Neurological Association, Chicago, IL | 08/2022 |
| Invited Symposia, Neurovascular and Retino-Vascular Changes in Animal Models of Pregnancy Disorders, Experimental Biology Meeting/Microcirculatory Society, Philadelphia, PA | 04/2022 |
| Platform Presentations, Career on “Pause”: Impact of the Pandemic on Early- to Mid-Career Women+ in Academic Neurology and Neuroscience, ANA 2021, Virtual | 10/2021 |
| State/Local Invited Seminars/Lectures, Preeclampsia and Cerebrovascular Disease: The Maternal Brain at Risk, UMMC, UMMC Maternal Fetal Medicine Fellow Lecture | 03/2021 |
| National and International Invited Seminars/Lectures, Neurovascular Abnormalities in Preeclampsia: Preclinical Investigations towards the Mechanisms, University of Minnesota Academic Health Center | 02/2021 |
| National and International Invited Seminars/Lectures, Role of Acid Sensing Ion Channels in Seizure Sensitivity during Placental Ischemia, Zooming in on Preeclampsia Seminar Series, Zoom (Virtual) | 12/2020 |
| National and International Invited Seminars/Lectures, Can Pregnancy Hurt Your Brain? Long-term effects of Preeclampsia, University of Kentucky, Doris Wilkinson Lecture | 12/2020 |
| Platform Presentations, Cerebrovascular Effects of Preeclampsia: Basic Aspects, AHA Scientific Sessions | 11/2020 |
| State/Local Invited Seminars/Lectures, Mechanisms for increased seizure sensitivity following utero-placental ischemia, UMMC, Department of Physiology | 12/2019 |
| Invited Symposia, Survived a Complicated Pregnancy? Maternal, Postpartum, and Fetal Cerebrovascular Risks, Experimental Biology/APS, Orlando, FL | 04/2019 |
| National and International Invited Seminars/Lectures, Does Placenta Health determine Cognitive Health in Mother and Offspring?, OUHSC, Oklahoma Center for Neuroscience | 03/2019 |
| Platform Presentations, Placental Ischemia Exposure leads to a Pro-Inflammatory Environment in Brains of Embryonic Day 19 Rat Offspring, Council on Hypertension, Chicago, IL | 09/2018 |
| Platform Presentations, Pregnancy and Preeclampsia I, Hypertension Scientific Sessions, Chicago, IL | 09/2018 |
| State/Local Invited Seminars/Lectures, Grant Writing Workshop (K99/R00 Award): Responding to Reviewers’ Comments, UMMC Office of Sponsored Programs, UMMC | 01/2018 |
| Campus Presentations, Maternal and perinatal cerebrovascular complications following placental ischemia, Department of Physiology Seminar, UMMC | 05/2017 |
| State/Local Invited Seminars/Lectures, Perinatal cerebrovascular injury following placental ischemia exposure, COBRE/MCOR Meeting, UMMC | 05/2017 |
| Platform Presentations, βENaC is required for placental vascular remodeling in mice., Experimental Biolofy/ APS, Chicago, IL | 04/2017 |
| Campus Presentation, Placental ischemia and perinatal cerebrovascular abnormalities, CRRC Work in Progress Meeting, UMMC | 10/2016 |
| Campus Presentation, Cerebrovascular abnormalities in preeclampsia: Identifying the mechanisms, Neurology Grand Rounds, UMMC | 03/2016 |
| National and International Invited Seminars/Lectures, Agonistic autoantibodies to Angiotensin II type 1 receptor contributes partly to placental ischemia-induced cerebrovascular abnormalities, Council on Hypertension Meeting, Washington, DC | 09/2015 |
| National and International Invited Seminars/Lectures, Hemeoxygenase-1 induction increases beta ENaC in ischemic placentas and cultured cytotrophoblasts, International Society for Hypertension, New Orleans, LA | 09/2013 |
| Poster Presentation, Pentylenetetrazol-Induced Seizures during Placental Ischemia: A Potential Model of Eclampsia?, 2015 Experimental Biology Meeting, Boston, MA | |
| Poster Presentation, Placental Ischemia Impairs Cerebral Blood Flow Autoregulation and Increases Blood-Brain Barrier Permeability in Pregnant Rats., 2015 Experimental Biology Meeting, Boston, MA | |
| Poster Presentation, Placental ischemia increases seizure susceptibility in pregnant rats., 2015 International Stroke Conference, Nashville, TN | |
| Platform Presentations, Placental ischemia impairs cerebral blood flow autoregulation and increases blood-brain barrier permeability in pregnant rats, Experimental Biology/ American Pysiological Society, Boston, MA | |
| National and International Invited Seminars/Lectures, Featured Topic: Cerebrovascular abnormalities in hypertensive diseases, 2015 Experimental Biology Meeting, Boston, MA | |
| National and International Invited Seminars/Lectures, Featured Topic: Vascular cognitive impairment: Emerging concepts and pathophysiology, 2013 Experimental Biology Meeting | |
| National and International Invited Seminars/Lectures, Post-doc to faculty transition, EB 2017 APS, Networking Breakfast |
Honors, Awards, and Recognition
| Wiley Research Hero Nominee, John Wiley & Sons | 2024 |
| Tenure, UMMC | 2023 |
| The Physiologist Cover Story, American Physiological Society | 2022 |
| Inductee, Sigma Xi Scientific Research Honor Society | 2022 |
| Nominee, Beacon Award, UMMC Office of Diversity and Inclusion | 2022 |
| Fellow of the American Heart Association, American Heart Association | 2021 |
| Women in Science Feature, Technology Networks | 2021 |
| Nominee, Beacon Award, UMMC | 2021 |
| Gold Award, UMMC Research Excellence Awards | 2020 |
| Silver Award, UMMC Research Excellence Awards | 2018 |
| Bronze Award, UMMC Research Excellence Awards | 2017 |
| APS/NIDDK Minority Travel Fellowship Award, Physiology & Gender Conference | 2015 |
| APS CNS Section Research Recognition Award, American Physiological Society | 2015 |
| ISH New Investigator Committee Travel Grant 2013, International Society of Hypertension | 2013 |
| Fleur L. Strand Professional Opportunity Award/ Caroline tum Suden Award, American Physiological Society | 2013 |
| Outstanding Dissertation Award, University of Oklahoma Health Sciences Center | 2012 |
| APS/NIDDK Minority Travel Fellowship Award, American Physiological Society | 2012 |
| APS/NIDDK Minority Travel Fellowship Award, American Physiological Society | 2011 |
| Travel Award Recipient, Oklahoma Center for Neuroscience Symposium | 2009 |
| Summa Cum Laude (GPA: 4.0), Fort Valley State University | 2007 |
| Psychology Departmental Award, Fort Valley State University | 2007 |
| First Prize Winner of Banks-Pierro-Rutland-Bellamy Social Sciences Colloquium, Fort Valley State University | 2007 |
| Presidential Scholar, Fort Valley State University | 2004 |
| Valedictorian, Portsmouth Secondary School, Dominica | 1998 |
| UMMC |
Professional Membership and Service
| ISTAART, Member | 2024 - Present |
| American Neurological Association, Fellow | 2023 - Present |
| Sigma Xi, Member | 2022 - Present |
| PROWESS, Member | 2018 - Present |
| International Society of Hypertension, Emerging Leader | 2018 - Present |
| Center for Scientific Review, Member, Early Career Reviewer Program | 2017 - 2019 |
| Director, CRRC Seminar Series | 2015 - 2017 |
| Microcirculatory Society, Member, Trainee Committee | 2015 - 2018 |
| International Society of Hypertension, Research Fellow | 2013 - 2017 |
| Microcirculatory Society, Member | 2012 - Present |
| American Physiological Society, Member | 2011 - Present |
| Society for Neuroscience, Member | 2008 - Present |
| Alpha Kappa Mu National Honor Society, Member | 2007 - Present |
| Pi Gamma Mu International Honor Society, Member | 2007 - Present |
| American Psychological Association, Member | 2006 - 2013 |
| American Heart Association, Member | |
| Society for Neuroscience, Member |
Committee Service
| PIN Admissions Committee, Chair | 2022 - Present |
| Communications Committee - Council on Hypertension, Member | 2022 - Present |
| NAS Faculty Search Committee, Member | 2021 - 2022 |
| Neurology Promotion & Tenure Committee, Member | 2021 - Present |
| Neurology Research Executive Committee, Member | 2019 - Present |
| Neurology Student Research, Chair | 2019 - Present |
| PIN Exceutive Committee, Member | 2019 - Present |
| APS Cardiovascular Section Awards Committee, Member | 2018 - 2021 |
| Microcirculatory Society Trainee Committee, Member | 2015 - 2018 |
| Neurology Education Committee, Member |
Community Service
| Word of Life Church, First Impression Team Member | 06/2017 - Present |
| PhUN Week (GWIMS), Highland Bluff Elementary School, Volunteer | 05/2016 - 05/2016 |
| PhUN Week, Boys & Girls Club, Volunteer | 03/2015 - 03/2015 |
| Discovery U, Volunteer | 03/2014 - 03/2014 |
| PhUN Week, Team Leader | 03/2013 - 03/2013 |
| PhUN Week, Volunteer | 03/2012 - 03/2012 |
| Ronald McDonald House, Volunteer | 04/2009 - 12/2009 |
| Mini Medical School (OUHSC), Student Volunteer | 08/2008 - 10/2010 |
Other Service
| European Research Council Grant Review | 05/2024 - Present |
| Genomics COBRE Pilot Grant Program | 03/2024 - Present |
| UMMC Intramural IRSP Pilot Grant Program | 03/2024 - Present |
| SHIFT Program (Meharry), Mentor | 02/2024 - Present |
| NIH Special Emphasis Panel on The Intersection of Sex and Gender Influences on Health and Disease | 02/2024 - Present |
| AHA Career Development Award Basic Sciences 1 Committee, Co-Chair | 02/2024 - Present |
| AHA Pre- and Post-doctoral Fellowship Clinical 2 Review Panel | 11/2023 - Present |
| NIH Special Emphasis Panel on The Intersection of Sex and Gender Influences on Health and Disease | 06/2023 - Present |
| Neurology Discovery and Innovation Grant (NDIG) Reviewer | 05/2023 - Present |
| AHA Transformational Project Award, Vascular 1 Review Panel | 05/2023 - Present |
| United Kingdom Research Institute, Development Pathways Funding Scheme | 12/2022 - Present |
| March of Dimes Discovery Research Grant Award Applications | 12/2022 - Present |
| AHA Pre and Postdoctoral Applications | 09/2022 - Present |
| IRSP Grant Review | 06/2022 - Present |
| External Reviewer, UNMC Center for Heart & Vascular Research Pilot Grant Program | 12/2021 - Present |
| Consulting Editor, AJP: Heart & Circ Physiology | 01/2021 - Present |
| Guest Editor, Cells | 12/2020 - Present |
| Co-Editor-in-Chief, Journal of Neuroscience Research | 2020 - Present |
| AHA Career Development Award Basic Sciences 1 | 11/2019 - Present |
| 2019 Hypertension Meeting CHAMP Mentor, CHAMP Mentor | 09/2019 - 09/2019 |
| Letter of Intent Reviewer, March of Dimes | 06/2019 - 06/2019 |
| Social Media Editor, Stroke | 04/2019 - 04/2021 |
| NIH Early Career Reviewer, PN Study Section | 02/2019 - 02/2019 |
| Guest Editor, Brain Sciences Journal | 2019 - 10/2019 |
| Career Development Award Basic Sciences 1, AHA | 12/2018 - 12/2018 |
| Subject Editor, Journal of Neuroscience Research | 09/2018 - 12/2019 |
| Career Development Award Basic Sciences 1, AHA | 02/2018 - 02/2018 |
| Ad hoc Reviewer, Perinatal COBRE Pilot Grant Program | 12/2017 - 12/2017 |
| Abstract Reviewer, International Stroke Conference | 09/2015 - Present |
| Letter of Intent Reviewer, AHA Innovative Project Award | 12/2019 |
| Peer Reviewer, Journal of Cerebral Blood Flow and Metabolism | |
| Peer Reviewer, Journal of Gerontology: Biological Sciences | |
| Peer Reviewer, Hypertension | |
| Peer Reviewer, AJP: Heart | |
| Peer Reviewer, PLoS One | |
| Peer Review, AJP: Cell | |
| Peer Review, AJP: Regulatory & Comparative Physiology | |
| Peer Review, Brain Behavior and Immunity |
Teaching Experience
| NSCI 720, Graduate, Course, Course Director, Journal Club | Fall 2025 |
| PHARM 724, Graduate, Lecture, Lecturer, Experimental Design and Methods | Spring 2022 |
| NSCI 708, Graduate, Course, Facilitator, Special Topics in Neuroscience | Summer 2022 |
| NSCI 798, Graduate, Course, Lab Director, Dissertation Research | Fall 2022 |
| NSCI 798, Graduate, Course, Lab Director, Dissertation Research | Summer 2022 |
| NSCI 798, Graduate, Course, Lab Director, Dissertation Research | Spring 2022 |
| ID709, Graduate, Lecture, Facilitator, Responsible Conduct of Research | Spring 2022 |
| MCCTR, Small Group, Facilitator, MCCTR Mentoring Academy | Annual 2022 |
| Postdoc, Small Group, Facilitator, Postdoc Responsible Conduct of Research | Annual 2022 |
| NSCI 798, Graduate, Course, Lab Director, Dissertation Research | Spring 2021 |
| ID 709, Graduate, Course, Facilitator, Responsible Conduct of Research | Spring 2021 |
| NSCI 708, Graduate, Course, Course Director, Special Topics in Neuroscience | Summer 2021 |
| PPP790, Lecture, Lecturer | Fall 2021 |
| MCCTR, Small Group, Facilitator, MCCTR Mentoring Academy | Annual 2021 |
| NSCI 798, Graduate, Course, Lab Director, Dissertation Research | Fall 2021 |
| NSCI 791, Graduate, Lab, Lab Director, Senior Lab Rotation | Spring 2020 |
| NSCI 791, Graduate, Lab, Lab Director, Senior Lab Rotation | Summer 2020 |
| NSCI 798, Graduate, Course, Lab Director, Dissertation Research | Fall 2020 |
| NSCI 708, Graduate, Course, Course Director, Special Topics in Neuroscience | Summer 2020 |
| ID 709, Graduate, Course, Facilitator, Responsible Conduct of Research | Spring 2020 |
| PPP 790, Course, Course Presenter | Fall 2020 |
| Course, Facilitator, Responsible Conduct of Research - Postdoc/Instructor | Fall 2020 |
| ID709, Graduate, Course, Facilitator, Responsible Conduct of Research | Spring 2019 |
| NSCI708, Graduate, Small Group, Facilitator, Special Topics in Neuroscience | Summer 2019 |
| PPP790, Course, Course Presenter | Fall 2019 |
| NSCI791, Graduate, Lab, Lab Director, Senior Lab Rotation | Summer 2019 |
| NSCI791, Graduate, Lab, Lab Director, Senior Lab Rotation | Fall 2019 |
| ID709, Graduate, Lecture, Facilitator, Responsible Conduct of Research | Spring 2018 |
| ID709, Graduate, Course, Facilitator, Responsible Conduct of Research | Spring 2017 - 2017 |
Directed Student Learning
| Supervised Research, Advised: Casey Young | 2025 - 2025 |
| Supervised Research, Advised: Piper Lind | 2025 - Present |
| Supervised Research, Advised: Sarah Broadaway | 2025 - Present |
| Supervised Research, Advised: Kendra Outlaw | 2025 - 2025 |
| Dissertation Committee Member, Advised: Jobin Babu | 2024 - Present |
| Supervised Research, Advised: Youness Touissi | 2023 - 2023 |
| Research Advisor, Advised: Karen Saffold | 2023 - Present |
| Research Advisor, Advised: Aspen Treadwell | 2023 - 2024 |
| Dissertation Committee Member, Advised: Jena' Mazique | 2023 - Present |
| Doctoral Advisory Committee Member, Advised: Jonna Smith | 2023 - Present |
| Supervised Research, Advised: Ahmya Clayton | 2023 - 2024 |
| Supervised Research, Advised: Simranjit Kaur | 2023 - Present |
| Research Advisor, Advised: Hadley Ewing | 2023 - 2023 |
| Research Advisor, Advised: Andrea Tall | 2023 - 2023 |
| Internship Advisor, Advised: Kennedi Stancil | 2022 - 2022 |
| Supervised Research, Advised: Mia McFadden | 2022 - 2022 |
| Supervised Research, Advised: Morgan Kendrick | 2022 - 2022 |
| Supervised Research, Advised: Zyon Davis | 2022 - Present |
| Dissertation Committee Member, Advised: Xing Fang | 2021 - 2023 |
| Dissertation Committee Member, Advised: Ubong Ekperikpe | 2021 - 2023 |
| Supervised Research, Advised: Kennedi Stancil | 2021 - Present |
| Dissertation Committee Chair, Advised: Maria Jones-Muhammad | 2020 - 2023 |
| Dissertation Committee Member, Advised: John Aaron Howell | 2019 - 2023 |
| Supervised Research, Advised: Ashley Griffin | 2019 - 2019 |
| Supervised Research, Advised: Ashtin Beckett | 2019 - Present |
| Internship Advisor, Advised: Akia Sherrod | 2019 - 2019 |
| Research Advisor, Advised: Maria Jones-Muhammad | 2019 - Present |
| Dissertation Committee Member, Advised: Kenji Maeda | 2018 - 2020 |
| Undergraduate Honors Thesis, Advised: Ahsia Clayton | 2018 - 2019 |
| Supervised Research, Advised: Kendra Stansak | 2018 - 2018 |
| Supervised Research, Advised: Ahsia Clayton | 2017 - 2017 |
| Supervised Research, Advised: Javarcia Ivory | 2015 - 2015 |
| Research Advisor, Advised: Goodness Adegbola | |
| Supervised Research, Advised: Youness Touissi | |
| Supervised Research, Advised: Karen Saffold | |
| Supervised Research, Advised: Jena' Mazique | |
| Supervised Research, Advised: Jon Person | |
| Supervised Research, Advised: Linda Zhang |
Fellows supervised
| T32 Trainee, Post-Doc Advisor, 0 fellows supervised | 02/2024 - Present |
| Post-Doc Advisor, 1 fellows supervised | 11/2021 - 01/2022 |
Residency Training
| Obstetrics & Gynecology, Research Advisor |