Journal Article |
| Pise-Masison CA, Rahman MA, Masison DC, Gutowska A, Moles R, Bissa M, Sarkis S, Schifanella L, Zhou T, Jones J, Jacobson S, Franchini G. Development and optimization of human T-cell leukemia virus-specific antibody-dependent cell-mediated cytotoxicity (ADCC) assay directed to the envelope protein J Virol. 2025 Mar 28:e0226824. | 2025 |
| Moles R, Omsland M, Pise-Masison CA, Subleski JJ, McVicar DW, Sarkis S, Gutowska A, Schifanella L, Doster M, Washington-Parks R, Ciminale V, Franchini G. HTLV-1 p13 Protein Hijacks Macrophage Polarization and Promotes T-Cell Recruitment Viruses. 2025 Mar 26;17(4):471. | 2025 |
| Rahman MA, Bissa M, Scinto H, Howe SE, Sarkis S, Ma ZM, Gutowska A, Jiang X, Luo CC, Schifanella L, Moles R, Silva de Castro I, Basu S, N'guessan KF, Williams LD, Becerra-Flores M, Doster MN, Hoang T, Choo-Wosoba H, Woode E, Sui Y, Tomaras GD, Paquin-Proulx D, Rao M, Talton JD, Kong XP, Zolla-Pazner S, Cardozo T, Franchini G, Berzofsky JA. Loss of HIV candidate vaccine efficacy in male macaques by mucosal nanoparticle immunization rescued by V2-specific response Nat Commun. 2024 Oct 22;15(1):9102. | 2024 |
| Gutowska A, Sarkis S, Rahman MA, Goldfarbmuren KC, Moles R, Bissa M, Doster M, Washington-Parks R, McKinnon K, Silva de Castro I, Schifanella L, Franchini G, Pise-Masison CA. Complete Rescue of HTLV-1p12KO Infectivity by Depletion of Monocytes Together with NK and CD8+ T Cells Pathogens. 2024 Mar 29;13(4):292. | 2024 |
| Bissa M, et al. In Vivo Treatment with Insulin-like Growth Factor 1 Reduces CCR5 Expression on Vaccine-Induced Activated CD4+ T-Cells Vaccines (Basel). 2023 Oct 30;11(11):1662. | 2023 |
| Rahman MA, Bissa M, Silva de Castro I, Helmold Hait S, Stamos JD, Bhuyan F, Hunegnaw R, Sarkis S, Gutowska A, Doster MN, Moles R, Hoang T, Miller Jenkins LM, Appella E, Venzon DJ, Choo-Wosoba H, Cardozo T, Baum MM, Appella DH, Robert-Guroff M, Franchini G. Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques. Nat Microbiol. 2023 Aug;8(8):1600. | 2023 |
| Rahman MA, Bissa M, Silva de Castro I, Helmold Hait S, Stamos JD, Bhuyan F, Hunegnaw R, Sarkis S, Gutowska A, Doster MN, Moles R, Hoang T, Miller Jenkins LM, Appella E, Venzon DJ, Choo-Wosoba H, Cardozo T, Baum MM, Appella DH, Robert-Guroff M, Franchini G. Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques Nat Microbiol. 2023 May;8(5):905-918. | 2023 |
| Bissa M, Kim S, Galli V, Fourati S, Sarkis S, Arakelyan A, de Castro IS, Rahman MA, Fujiwara S, Vaccari M, Tomalka JA, Stamos JD, Schifanella L, Gorini G, Moles R, Gutowska A, Ferrari G, Lobanov A, Montefiori DC, Nelson GW, Cam MC, Chakhtoura M, Haddad EK, Doster MN, McKinnon K, Brown S, Venzon DJ, Choo-Wosoba H, Breed MW, Killoran KE, Kramer J, Margolis L, Sekaly RP, Hager GL, Franchini G. HIV vaccine candidate efficacy in female macaques mediated by cAMP-dependent efferocytosis and V2-specific ADCC Nat Commun. 2023 Feb 2;14(1):575. | 2023 |
| Gutowska A, et al. Transient viral activation in human T cell leukemia virus type 1-infected macaques treated with Pomalidomide Front Med (Lausanne). 2022 May 5:9:897264. | 2022 |
| Moles R, Sarkis S, Galli V, Omsland M, Artesi M, Bissa M, McKinnon K, Brown S, Hahaut V, Washington-Parks R, Welsh J, Venzon DJ, Gutowska A, Doster MN, Breed MW, Killoran KE, Kramer J, Jones J, Moniuszko M, Van den Broeke A, Pise-Masison CA, Franchini G. NK cells and monocytes modulate primary HTLV-1 infection PLoS Pathog. 2022 Apr 4;18(4):e1010416 | 2022 |
| Bellon M, Moles R, Chaib-Mezrag H, Pancewicz J, Nicot C. JAG1 overexpression contributes to Notch1 signaling and the migration of HTLV-1-transformed ATL cells J Hematol Oncol. 2018 Sep 19;11(1):119. | 2018 |
| Moles R, Bai XT, Chaib-Mezrag H, Nicot C. WRN-targeted therapy using inhibitors NSC 19630 and NSC 617145 induce apoptosis in HTLV-1-transformed adult T-cell leukemia cells J Hematol Oncol. 2016 Nov 9;9(1):121. | 2016 |
| Yeh CH, Bai XT, Moles R, Ratner L, Waldmann TA, Watanabe T, Nicot C. Mutation of epigenetic regulators TET2 and MLL3 in patients with HTLV-I-induced acute adult T-cell leukemia Mol Cancer. 2016 Feb 16;15:15. | 2016 |
| Bai XT, Moles R, Chaib-Mezrag H, Nicot C. Small PARP inhibitor PJ-34 induces cell cycle arrest and apoptosis of adult T-cell leukemia cells Journal of hematology & oncology 8, 1-12 | 2015 |
| Moles R, Bellon M, Nicot C. STAT1: A novel target of miR-150 and miR-223 is involved in the proliferation of HTLV-I–transformed and ATL cells Neoplasia. 2015 May;17(5):449-62. | 2015 |
Review Article |
| Echevarria-Lima J, Moles R. Monocyte and Macrophage Functions in Oncogenic Viral Infections. Viruses. 2024 Oct 15;16(10):1612. | 2024 |
| Omsland M, Silic-Benussi M, Moles R, Sarkis S, Purcell DFJ, Yurick D, Khoury G, D'Agostino DM, Ciminale V, Franchini G. Functional properties and sequence variation of HTLV-1 p13 Retrovirology. 2020 May 12;17(1):11. | 2020 |
| Moles R, Sarkis S, Galli V, Omsland M, Purcell DFJ, Yurick D, Khoury G, Pise-Masison CA, Franchini G. p30 protein: a critical regulator of HTLV-1 viral latency and host immunity Retrovirology. 2019 Dec 18;16(1):42. | 2019 |
| Sarkis S, Galli V, Moles R, Yurick D, Khoury G, Purcell DFJ, Franchini G, Pise-Masison CA. Role of HTLV-1 orf-I encoded proteins in viral transmission and persistence Retrovirology. 2019 Dec 18;16(1):43. | 2019 |
| Moles R. MicroRNAs-based therapy: a novel and promising strategy for cancer treatment Microrna. 2017 Aug 16;6(2):102-109. | 2017 |
| Yeh CH, Moles R, Nicot C. Clinical significance of microRNAs in chronic and acute human leukemia. Mol Cancer. 2016 May 14;15(1):37. | 2016 |
| Moles R, Nicot C. The Emerging Role of miRNAs in HTLV-1 Infection and ATLL Pathogenesis 26205403 | 2015 |
| Sapone A, Canistro D, Melega S, Moles R, Vivarelli F, Paolini M. On enzyme-based anticancer molecular dietary manipulations. J Biomed Biotechnol. 2012;2012:790987. | 2012 |
Abstracts |
| Rahman, MA; Scinto, H; Bissa, M; Howe, SE; Sarkis, S; Jiang, X; Luo, CC; Gutowska, A; Schifanella, L; Moles, R; de Castro, IS; Flores, MB et al. V2-specific responses rescues SIV vaccine efficacy decreased by mucosal immunization with nanoparticles | 2024 |
| A Sapone, D Canistro, G Potenza, F Vivarelli, R Moles, M Paolini Modulazione della superfamiglia CYP in Dreissena polymorpha esposte ad acqua del Lago Trasimeno trattata con differenti disinfettanti. 16° Congresso Nazionale Società Italiana di Tossicologia | 2012 |
| D Fujikawa, R Moles, M Omsland, D Purcell, V Galli, G Franchini A-102 Do biological differences exist between HTLV-1A and HTLV-1C? JAIDS Journal of Acquired Immune Deficiency Syndromes 81, 30 | |
Dissertation |
| Moles R. CELLULAR PATHWAY DEREGULATION AND POTENTIAL TARGETED THERAPY FOR ADULT T-CELL LEUKEMIA | 2017 |
