Joe C. Files, MD
PROFESSOR EMERITUS
Department:
SOM-Medicine-HEM
Email:
jfiles@umc.edu
Education
| University of Washington School of Medicine, Hematology | 1979 |
| University of Mississippi School of Medicine, Chief Resident, Medicine | 1976 |
| University of Mississippi School of Medicine, Medicine | 1975 |
| University of Mississippi School of Medicine, Internship (Straight Medicine) | 1973 |
| University of Mississippi School of Medicine, MD, Medicine | 1972 |
| University of Mississippi, BS | 1969 |
Specialty Certification Licensure
| Certification, Hematology, American Board of Internal Medicine | 1980 - Present |
| Licensure, Washington Medical License, State Board of Medical Licensure | 1977 - Present |
| Certification, Internal Medicine, American Board of Internal Medicine | 1976 - Present |
| Licensure, Mississippi Medical License, State Board of Medical Licensure | 1972 - 06/2011 |
Academic Appointments or Other Previous Appointments
| University of Mississippi Medical Center, School of Medicine, Department of Medicine | 2012 |
| Associate Chairman, University of Mississippi Medical Center, School of Medicine, Department of Medicine | 1998 - 2011 |
| University of Mississippi Medical Center, School of Medicine, Department of Medicine | 1995 - 12/2011 |
| University of Mississippi Medical Center, School of Medicine, Department of Medicine | 1993 - 2011 |
| Professor, University of Mississippi Medical Center, School of Medicine, Department of Medicine | 1992 - 2011 |
| University of Mississippi Medical Center, School of Medicine, Department of Cancer Institute | 2003 - 2009 |
| Associate Professor, School of , Department of Medicine | 07/1986 - 06/1992 |
| Assistant Professor, School of , Department of Medicine | 08/1979 - 06/1986 |
Publications
Journal Article | |
| Reich D, Nalls M, Kao WHL Akylbekova EL, Tandon A, Patterson N, Mullikin J, Hsueh W, Cheng C, Coresh J, Boerwinkle E, Li M, Waliszewka A, Neubauer J, Li R, Leak TS, Ekunwe L, Files JC, Hardy CL, Zmuda JM, Taylor HA, Ziv E, Harris TB, Wilson JG. Reduced neutrophil count in people of African descent is due to a regulatory variant in the duffy antigen receptor for chemokines gene. PlosS Genetics. 2009; 5(1): | 2009 |
| Martin JN, Briery CM, Rose CH, Owens MT, Bofill JA, Files JC. Postpartum plasma exchange as adjunctive therapy for severe acute fatty liver of pregnancy J Clinical Apheresis. 2008;23:138-143 | 2008 |
| Nalls MA, Wilson JG, Patterson NJ, Tandon A, Zmuda JM, Huntsman S, Garcia M, Hu D, Li R, Beamer BA, Patel KV, Akylbekova EL, Files JC, Hardy CL, Buxbaum SG, Taylor HA, Reich D, Harris TB, Ziv E. Admixture mapping of white cell count: genetic locus responsible for lower white blood cell count in the heath ABC and Jackson Heart Studies AJHG. 2008;82:81-87. | 2008 |
| Bigelow C, Elkins S, Hardy C, Files J. Allotransplantation with reduced intensity conditioning that includes alemtuzmab lessens incidence of relapse and transplant-related mortality in patients with high-risk myeloid diseases. J Invest Med. 2006; 54(1): 5272 | 2006 |
| Bigelow C, Elkins S, Herrin V, Hardy C, Files J. Reduced intensity conditioning regimens with Alemtuzumab result in low treatment-related mortality and low relapse rate in unrelated and related allotransplantation recipients. Blood. 2006; 108(11):a5253 | 2006 |
| Bigelow C, Elkins S, Hardy C, Files J. Allotransplantation with reduced intensity conditioning that includes alemtuzumab lessens transplant-related mortality is a useful treatment for high-risk myeloid diseases. Biol Blood Marrow Trans. 2006; 12(2):46 | 2006 |
| Bigelow CL, Elkins S, Hardy CL, Files JC. Allotransplantation with reduced intensity conditioning regimens modified to lessen transplant-related mortality is a useful treatment for high risk myeloid diseases. Blood. 2005; 106:5328 | 2005 |
| Bigelow CL, Elkins S, Hardy CL, Files JC. Less transplant-related mortality with variable intensity conditioning than non-myeloablative conditioning in unrelated and related allogenic transplant recipients. Biol Blood Marrow Transp. 2005; 11:(2)34 | 2005 |
| Duhe RJ, Faruque F, Walker LA, Files JC, Taggart A. The convergence of science and technology in Mississippi: advancing the frontiers of biomedicine. J MS Acad Sci. 2005; 50(1):14-28 | 2005 |
| Bigelow C, Elkins S, Hardy C, Files J. Variable intensity conditioning is associated with less transplant-related mortality than non-myeloablative conditioning in unrelated and related allogenic transplan recipents. J Invest Med. 2005; 53(1): S276 | 2005 |
| Bigelow C, Elkins S. Hardy C, Files J. Less transplant related mortality with variable intensity conditioning in unrelated and related adult allogenic transplant recipients. Blood, 2004; 104:345b | 2004 |
| Bigelow C, Elkins S, Hardy C, Files J. Variable intensity conditioning with durable engraftment and less graft versus host disease. J Invest Med. 2004; 52(1):S272 | 2004 |
| Bigelow C, Elkins S, Hardy C, Files J. Variable intesity conditioning with durable engrafment and less graft versus host disease. J Invest Med, 2004; 52(1): S272 | 2004 |
| Bigelow C, Elkins S, Hardy C, Files J. Outcomes of unrelated PBSC transplantation in adult Cuacasian and African American patients: one center's experience. J Invest Med. 2003; 51:S264 | 2003 |
| McCollum A, Bigelow CL, Elkins SL, Hardy CL, Files JC. Unusual skin Lesions in chronic myelomonocytic leukemia. South Med J. 2003; 96(7):681-684 | 2003 |
| Bigelow CL, Elkins S, Megason GC, Hardy CL, Files JC. Effect on platelet and neutrophil recovery of administration of filgrastim post transplant in autologous transplant recipients. Blood, 2003;102(11): 438b | 2003 |
| Bigelow CL, Elkins S, Megason GC, Hardy CL, Files JC. Variable intesity conditioning with durable engraftment and less graft versus host disease in recipients of unrelated transplants. Blood, 2003; 102(11): 428b | 2003 |
Presentations
| Scientific Presentations, A case report of adult T cell leukemia., Southern Society of Clinical Investigation, New Orleans, LA | 02/2010 |
| Scientific Presentations, Acquired amegakaryocytic thrombocytopenia: A case series and review of the literature., Southern Society of Clinical Investigation, New Orleans, LA | 02/2010 |
| Scientific Presentations, Suppression for the suppressed: Aplastic anemia without a sibling donor match., Southern Society of Clinical Investigation, New Orleans, LA | 02/2010 |
| Scientific Presentations, Hodgkin's lymphoma presenting as hematuria, Southern Society for Clinical Investigation, New Orleans, LA | 02/2009 |
| Scientific Presentations, Pseudothrombocytopenia and platelet dysfunction: a diagnostic dilemma, Southern Society for Clinical Investigation, New Orleans, LA | 02/2009 |
| State/Local Invited Seminars/Lectures, Hypercoagulation syndrome, St. Dominic Neuroscience Cent's "NeuroScience in the Heart of the Delta", Greenwood, MS | 2008 |
| State/Local Invited Seminars/Lectures, An update on the management of lymphomas, Oncology Best Practices, Ridgeland, MS | 03/2007 |
| Poster Presentation, Alemtuzumab dosing by recipient body weight is important for reduced intensity conditioning in allogeneic transplantation, Southern Society for Clinical Investigation, New Orleans, LA | 02/2007 |
| Poster Presentation, Reduced intensity conditioning using alemtuzumab in allogeneic hematopoietic transplantation, Southern Society of Clinical Investigation, New Orleans, LA | 02/2007 |
| Poster Presentation, Thromboembolism in multiple myeloma patinets receiving thalidomide combination chemotherapy, Southern Society for Clinical Investigation, New Orleans, LA | 02/2007 |
| Poster Presentation, Unusual presentation of diffuse large B-cell lymphoma, Southern Society for Clinical Investigation, New Orleans, LA | 02/2007 |
| State/Local Invited Seminars/Lectures, Advances in Anticoagulation for the management of venous thromboembolic disease and heparin-induced thrombocytopenia., Oxford, MS | 10/2006 |
| State/Local Invited Seminars/Lectures, Stem Cell Transplant, Meridian, MS | 06/2006 |
| State/Local Invited Seminars/Lectures, Advances in anticoagulation for the management of venous thromboembolic disease and heparin-induced thrombocytopenia., Jackson, MS | 05/2006 |
| State/Local Invited Seminars/Lectures, Recent Clinical trials with antithrombotic drugs., Central Mississippi Medical Center, Jackson, MS | 04/2006 |
| State/Local Invited Seminars/Lectures, Advances in anticoagulation for the management of venous thromboembolic disease and heparin- induced thrombocytopenia., Canebreak Country Club, Hattiesburg, MS | 03/2006 |
| Regional Invited Seminars/Lectures, Allotransplantation with reduced intensity conditioning that includes alemtuzumab lessens incidence of relapse and transplant-related mortality in patients with high-risk myeloid diseases., Southern Society for Clinical Investigation, Atlanta, GA | 03/2006 |
| National and International Invited Seminars/Lectures, Allotransplantation with reduced intensity conditioning that includes alemtuzumab lessens transplant-related mortality and incidence of relapse in patients with high-risk myeloid disease., Tandem Bone Marrow transplant Meettings, Honolulu, Hawaii | 02/2006 |
| National and International Invited Seminars/Lectures, Less transplant-related mortality with variable intensity conditioning than non-myeloablative conditioning in unrelated and related adult allogenic transplant recipients., Tandem Bone Marrow Transplant Meetings, Keystone, MO | 02/2006 |
| State/Local Invited Seminars/Lectures, Hypercoagulation Syndrome., St. Dominic Neuroscience Center's "NeuroScience in the Heart of the Delta", Greenwood, MS | 01/2006 |
| State/Local Invited Seminars/Lectures, Bone Marrow Transplantation with Refractory Crohn's Disease., Jackson Gut Club, jackson, MS | 10/2005 |
| State/Local Invited Seminars/Lectures, Advances in Anticoagulation for the Management of Venous Thromboembolic Disease and Heparin-induced Thrombocytopenia (HIT): Diagnosis and Treatment Options., GlaxoSmithKline Sponsored Non-Independent Speaker Program, Jackson, MS | 06/2005 |
| State/Local Invited Seminars/Lectures, Variable Intensity Conditioning is Associated with Less Transplant Related Mortality than Non-myeloablative Conditioning in Unrelated and Related Allogenic Transplant Recipients., UMC Department of Medicine Research Day, Jackson, MS | 05/2005 |
| Regional Invited Seminars/Lectures, Variable Intensity Conditioning is Associated with Less Transplant Related Mortality than Non-myeloablative Conditioning in Unrelated and Related Allogenic Transplant Recipients., Southern Society for Clinical Invstigation, New Orleans, LA | 02/2005 |
| National and International Invited Seminars/Lectures, Less Transplant-Related Mortality with Variable Intensity Conditioning than Non-myeloablative Conditioning in Unrelated and Related Adult Allogenic Transplant Recipients., Tandem Bone Marrow Transplant Meetings, Keyston, CO | 02/2005 |
| National and International Invited Seminars/Lectures, Variable Intensity Conditioning is Associated with Less Transplant Related Mortality than Non-myeloablative Conditioning in Unrelated and Related Allogenic Transplant Recipients., NMDP Annual Council Meeting, Minneapolis, MN | 10/2004 |
| State/Local Invited Seminars/Lectures, Anemia, Family Practice Update, Jackson, MS | 04/2003 |
| State/Local Invited Seminars/Lectures, New Options in Bone Marrow Transplantation., MSCLS/LACLS Annual Meeting, Jackson, MS | 04/2002 |
| State/Local Invited Seminars/Lectures, Symposium on the Scientific, Ethical, Legal, and Societal Implications of Stem Cell Research; Panel Discussant., University of Mississippi, Oxford, MS | 02/2002 |
| National and International Invited Seminars/Lectures, Increased Incidence of Gastrointestinal Tract GVHD in Non-Myeloablated Recipients of Unrelated Donor Hematopoietic Cells., 2001 National Marrow Donor Program Council Meeting, Minneapolis, MN | 11/2001 |
| State/Local Invited Seminars/Lectures, Heparin Induced Thrombocytopenia (HIT) Diagnosis and New Treatments., GlaxoSmithKline lecture, Jackson, MS | 10/2001 |
| State/Local Invited Seminars/Lectures, Hypercoagulable States., St. Dominic Neuroscience Update, Biloxi, MS | 07/2001 |
| State/Local Invited Seminars/Lectures, Anti-Coagulant and Anti-Platelet Therapies., Family Practice Update 2001, Jackson, MS | 04/2001 |
Honors, Awards, and Recognition
| Mastership, American College of Physicians | 2011 |
| America's Top Doctors, Castle Connolly | 2010 |
| Guide to America's Top Physicians | 2009 |
| Diagnosis and Treatment of Cancer Award, MS Partnership for Comprehensive Cancer Control | 2009 |
| Jaems L. Achord Physician Award, Department of Medicine | 2008 |
| America's Top Doctors for Cancer, Castle Connolly | 2008 |
| Laureate Award, MS Chapter American College of Physicians | 2008 |
| Who's Who Among Executives and Professionals | 2008 |
| International Health Professional of the Year Award | 2007 |
| Who's Who among Professionals in Research, Medicine and Healthcare, Cambridge | 2006 |
| Best Doctors in America | 2005 |
| Who's Who in Medical Sciences Education | 2005 |
| Who's Who in the World | 2005 |
| Machester Who's Who Among Executives and Professionals in Healthcare | 2004 |
| Guide to America's Top Physicians | 2003 |
| The National Register's Who's Who | 2001 |
| Marquis Who's who | 1999 |
| The Best Doctors in America: Southeast Region | 1996 |
Professional Membership and Service
| Public Health Experts Exchange Subcommittee, Member | 2012 - Present |
| American College of Physicians, Council member, Advisory Council | 2009 - Present |
| American College of Physicians, Committee member, Finance Committee | 2009 |
| American College of Physicians, Committee member, Advisory Committee | 2009 |
| American College of Physicians, Committee Chair, Nomination Committee | 2007 - 2008 |
| American College of Physicians, Committee member, Health and Public Policy Committee | 2002 - 2005 |
| American College of Physicians, Governor, Board of Governors | 2001 - 2005 |
| Southern Society for Clinical Investigation, Member | 1999 - 2011 |
| American Society for Blood and Marrow Transplantation, Member | 1994 - 2011 |
| MS Carrier Advisory Committee, Member | 1992 - 2011 |
| Southwest Oncology Group, Committee Member, Myeloma committee | 1983 - 2011 |
| Southwest Oncology Group, Committee Member, Lymphoma Committee | 1983 - 2011 |
| American Society of Hematology, Member | 1982 - Present |
| Mississippi State Medical Association, Member | 1982 - Present |
| American College of Physicians, Member | 1981 - Present |
| American College of Physicians, Fellow | 1981 - 1985 |
| Southwest Oncology Group, Member | 1979 - 2011 |
Committee Service
| Critical Care- Transfusion Steering Group, Member | 2010 - 2011 |
| Medical Center- Human Embryonic Stem Cell Oversight Committee, Chair | 2010 - 2011 |
| Medical Center - Centers and Institutes, Member | 2006 - 2009 |
| Public Health Tracking and Liaison Committee, Member | 2006 - 2006 |
| Medical Center - Faculty and Staff Recognition, Member | 2005 - 2011 |
| Biochemistry Committee, Member | 2004 - 2004 |
| Pediatric Hematology Committee, Member | 2004 - 2004 |
| Development Director Committee, Member | 2003 - 2007 |
| Medical Center - Cancer Institute Steering, Chair | 2002 - 2011 |
| School of Medicine- Promotions and Tenure Committee, Member | 2002 - 2011 |
| Radiation Oncology Search Advisory Committee, Member | 2002 - 2008 |
| Medical Center - Academic Council, Chair | 2002 - 2002 |
| VA Medical Center Search Advisory Committee | 2001 - 2001 |
| Medical Center - Academic Freedom And, Chair | 2000 - 2011 |
| UMC Cancer Center Development Task Force Committee, Vice Chair | 2000 - 2003 |
| School Of Medicine - Promotions (Clinical), Chair | 1995 - 2011 |
| Graduate Medical Education Curriculum Committee, Member | 1994 - 2007 |
| Clinical Cancer Committee, Member | 1990 - 2004 |
| American Board of Internal Medicine Committee, Member | 1982 - 2011 |
Other Service
| Department of Medicine Contribution Committee, Chairman | 2010 - 2011 |
| Department of Medicine Continuing Medical Education Conference Committee, Member | 2009 - 2011 |
| Department of Medicine Awards Committee, Chairman | 2006 - 2011 |
| Department of Medicine Benchmarking Committee, Chairman | 2006 - 2008 |
| Department of Medicine Executive Council, Chairman | 2004 - 2004 |
| Department of Medicine Alumni Committee | 2003 - 2011 |
| Faculty Development Committee | 2001 - 2011 |
| Department of Medicine Compliance Oversight Committee, Chairman | 2001 - 2002 |
| Department of Medicine Education Council, Member | 1998 - 2011 |
| Department Medicine Education Council, Chairman | 1998 - 2004 |
| Medicine House Officer Selection Committee, Member | 1994 - 2011 |
| Department of Medicine Compliance Oversight Committee, Member | 1994 - 2002 |
Teaching Experience
| 621, Medicine, Course, Lecturer, Introduction to Clinical Medicine | Fall 2010 |
Fellows supervised
| Hematology/Oncology Fellowship, Training Faculty, 8 fellows supervised | 01/1979 - Present |
Residency Training
| Internal Medicine Residency, Attending Physician | 1979 - 2011 |