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Insulin-Like Growth Factor Binding Protein - 3 (IGFBP - 3)

Test Name:Insulin - Like Growth Factor Binding Protein - 3 (IGFBP - 3)
Epic Order Code:LAB5236  
CPT Code:83519  
Specimen(s) Type:Serum, 0.5 mL  
Acceptable Container(s):Tops are gold and red.
Testing Schedule:Monday-Friday
Turn Around Time:STAT: NA  
 Routine: 4-8 days
Collection Information:No special patient preparation is required. Obtain by standard collection procedures.
Transport Information:Deliver to lab immediately. All specimens must be signed into the laboratory.
Reference Clients:If unable to deliver to the lab within 1 hour, centrifuge the specimen and remove serum from the red cells. Store and transport at 2-8° C within 7 days. If longer storage is required, store and transport at -20° C for up to 6 months.
Causes for Rejection:Improperly labeled, incorrect container, contaminated, insufficient volume, incorrect/delay in transport, gross hemolysis or lipemia.
Reference Range:See patient report
Additional Information:Insulin-like growth factor binding proteins bind IGF-I and IGF-II with high affinity but do not bind insulin. Of the six distinct IGF binding proteins structurally characterized at this time, IGFBP-3 has been shown to be the major carrier of the IGFs, transporting approximately 95% of circulating IGF-I and IGF-II.
 The IGFBP-3 assay is useful in assessing nutritional status, since IGFBP-3 decreases during both caloric and protein restriction.