Faculty Scholarship

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Faculty Scholarship

The Faculty Scholarship webpage is designed to share the news of faculty accomplishments in medical education including publications, conference presentations, and grants. The webpage may also serve as a resource for faculty looking to identify collaborators with shared research interests. Entries are accepted throughout the academic year, and the page is updated monthly.

August 2020 features:

Grants

  1. Brian Tieu was awarded a $2000 grant for research by Southern Dames of Mississippi in June 2020.

  2. IMPACT the RACE: Improved Primary Care for the Rural Community through Medical Education, a Health Resources and Services Administration (HRSA) grant, was awarded to the School of Medicine ($1.75 million for FY20-21 with $5.25 million recommended for future support). IMPACT the RACE is designed to enhance the education of all medical students to encourage them to choose residencies and careers in primary care in rural communities in Mississippi. Project activities include the development of community-based educational activities for medical students, support rural student recruitment and retention programs, development of extended rural community-based training activities, creation of a monitoring and advising system, training of UMMC and affiliate faculty, and the development of partnerships and affiliate faculty network. Dr. Loretta Jackson-Williams is the principal investigator. 

Publications

  1. Busche, K., Elks, M. L., Hanson, J. T., Jackson-Williams, L., Manuel, R. S., Parsons, W. L., Wofsy, D., Yuan, K. The Validity of Scores from the New MCAT Exam in Predicting Student Perforamnce: Results from a Multisite Study. Academic Medicine. 95(3): 387-395, March 2020. 
  2. Garg, T., Desai, A., Gala, K., Warawdekar, G., Tavri, S., (2020) Interventional Radiology Preparedness During Coronavirus Disease (COVID-19) Pandemic. Indian Journal of Radiology and Imaging.

    This is a review article about state of affairs of the COVID-19 pandemic in India, and guidelines for IR departments across of the country to prepare adequately for a surge.
  3. Jackson-Williams, L., The University of Mississippi School of Medicine, Academic Medicine, Volume 95, No. 9, September Supplement 2020.

    This article provides an overview of the University of Mississippi’s medical education program. It includes key features of the curriculum such as a description of the curriculum, curriculum changes since 2010, pedagogies, and clinical experiences. A snapshot of facts for the School of Medicine is also provided.

  4. Le H., Shue A., Freedman S., The Shrinking Eye: Dimensional Changes in the Young Child’s Eye after Glaucoma Drainage Device Implantation for Refractory Childhood Glaucoma. Journal of AAPOS. 2020 Apr;24(2):84.e1-84.e4. doi: 10.1016/j.jaapos.2019.12.011.  PMID: 32092365.

    This study was designed to investigate the magnitude of reduction in the axial length (AL) and corneal diameter following glaucoma drainage device (GDD) placement and intraocular pressure (IOP) reduction in glaucoma patients <3 years of age at surgery. In this study cohort, reduction in AL, corneal diameter, and cup:disk ratio was found to be correlated with reduced IOP after GDD placement. This result merits consideration during surgical planning for glaucoma patients <3 years of age.

  5. Liu, Y., Feng K., Jiang H., Hu F., Gao J., Zhang W., Zhang W., Huang B., Brant R., Zhang C., Yan H., Characteristics and Treatments of Ocular Blast Injury in Tianjin Explosion in China. BMC Ophthalmology. 2020 May 6; 20(1):185. doi: 10.1186/s12886-020-01448-3. PMID: 32375694.  PMCID: PMC7203803.

    Grant Support: (81830026/National Natural Science Foundation of China; 18ZXDBSY00030/Natural Science Foundation of Tianjin)

    The study was to investigate the healing process and functional recovery of neuroretina after idiopathic macular hole surgery, as well as analyzing the influencing factors.  Various ocular injuries were commonly in the casualties of blast, in which open-globe injuries have worst visual prognosis. OTS is a valid approach for evaluation of prognosis and optimizing the therapeutic strategies subsequently in the massive casualty. Intense rescue and careful examination, proper surgery should be performed correctly to rescue patients.

  6. McDonald, Tyler C., Drake, Luke C., Replogle, William H., Graves, Matthew L., Brooks, Jaysson T., Barriers to Increasing Diversity in Orthopaedics, JBJS Open Access: April-June 2020 - Volume 5 - Issue 2.

  7. Penman, Alan D., Crowder, Kimberly, Watkins, William, 50 Studies Every Ophthalmologist Should Know. Oxford University press, 2020.

    The book, 50 Studies Every Ophthalmologist Should Know, presents key studies that have shaped the practice of ophthalmology. Selected using a rigorous methodology, emphasis has been placed on landmark studies, which have influenced current ophthalmology practice guidelines. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for ophthalmologists, especially those in training or preparing for board review, as well as anyone who wants to learn more about the data behind clinical practice.

    This article provides the residency program perspective in an effort to determine what orthopaedic residency program directors and coordinators believe are the barriers to improving diversity at their own programs. The top three barriers to increasing racial/ethnic diversity included: (1) not having enough minority faculty, which may deter minority applicants, (2) consistently high ranking of minority applicants but not matching them, and (3) not enough minority applicants.

  8. Wang T., Li J., Xie R., Want J., Zhang W., Jiang F., Du M., Want X., Huang B., Brant R., Zhang C., Yan H., Intraocular Tumour Necrosis Factor Ligand Related Molecule 1 A Links Disease Progression of Proliferative Diabetic Retinopathy after Primary Vitrectomy. Clinical and Experimental Pharmacology & Physiology. 2020 Jun; 47(6):966-976.  doi: 10.1111/1440-1681.13284.  PMID: 32064668.

    Grant Support: (18ZXDBSY00030/Natural Science Foundation of Tianjin City; 31871184/National Natural Science Foundation of China; 81830026/National Natural Science Foundation of China)

    This study aims to examine levels of TL1A in serum and intraocular fluid in patients with proliferative diabetic retinopathy (PDR), and to explore the correlation of intraocular TL1A with the prognosis of PDR progression after primary vitrectomy. Tumour necrosis factor ligand related molecule 1 A (TL1A), a member of tumour necrosis factor superfamily, has been identified as a crucial regulator for vascular homeostasis and inflammation. However, the function of TL1A in diabetic retinopathy (DR) is largely unknown. TL1A and multiple inflammatory cytokines were highly enriched in the intraocular fluid of PDR patients compared with the controls. Lower levels of intraocular TL1A were associated with development of PDR complications after primary PPV and might be used as prognostic factor in predicting the vitrectomy outcome in PDR patients.

  9. Zhang W., Han H., Feng K., Wang X., Du M., Meng X., Liu Y., Huang B., Brant R., Yan H., Is it Necessary to Use Tobramycin-dexamethasone Eye Ointment Prophylactically in Eyes at the End of Intraocular Surgery?. BMC Ophthalmology. 2020 May 27;20(1):208. doi: 10.1186/s12886-020-01476-z. PMID: 32460732. PMCID: PMC7254748.

    Grant Support: (81830026/National Natural Science Foundation of China; 31871184/National Natural Science Foundation of China; 81800815/National Natural Science Foundation of China)

    This study aimed to explore the necessity of using ocular tobramycin-dexamethasone prophylactically at the end of intraocular surgery.  We did not observe a statistically significant difference in the incidence of endophthalmitis in patients with or without prophylactic tobramycin-dexamethasone eye ointment. A tobramycin-dexamethasone eye ointment seemed to increase some side effects such as eye secretions increasing and foreign body feeling.

  10. Zhu X., Wang J., Li J., Chen H., Huang B., Yan H., The Healing Process and Functional Recovery of Neuroretina after Idiopathic Macular Hole Surgery without Internal Limiting Membrane Reversal Tamponade. Journal of Ophthalmology. 4 May 2020:2478943. doi: 10.1155/2020/2478943. PMID: 32454986.  PMCID: PMC7222536.

    The study was to investigate the healing process and functional recovery of neuroretina after idiopathic macular hole surgery, as well as analyzing the influencing factors. Full-thickness IMHs could achieve anatomic closure 3 to 5 days after surgery with first-step inner retina tissue bridging. Otherwise, they were not able to achieve hole closure and opened to larger holes about two weeks postoperatively. Macular hole diameter was an important factor affecting the healing of the holes. The delayed restoration of fovea detachment and ellipsoid area deficiency were responsible for poor vision outcomes after surgery.

Trials

  1. Ajinkya Desai, Principal Investigator, C-TRACT Trial: An NIH funded multi-center randomized controlled trial aimed at assessing the efficacy of endovascular intervention in the treatment of post-thrombotic syndrome (from chronic DVT). University of Mississippi is one of the sites.

  2. In 2014, the AAMC formed the MCAT Validity Committee (MVC) to evaluate the validity of scores from the new MCAT exam. The committee comprises representatives from 16 U.S. and two Canadian medical schools and two pre-health advisors serving in current or previous leadership roles with the National Association of Advisors for the Health Professsions. The UMMC School of Medicine is one of the 16 U.S. medical schools. Faculty participating in the study include Demondes Haynes and Loretta Jackson-Williams. The MVC is evaluating evidence about the fairness, impact, use, and predictive validity of scores from the new MCAT exam, which is called for by professional testing standards and will form the foundation for evaluating the soundness of interpretations of these scores for use in admissions.