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Merry Lindsey, PhD

Professor of Physiology and Medicine (Cardiology)
Director, Mississippi Center for Heart Research
Office: G351-04
Lab: G364/74
(601) 815-1329
Lab: (601) 984-1824 or (601) 815-0816
Email: mllindsey@umc.edu

Areas of Expertise

  • General: Cardiovascular physiology, proteomics
  • Specific: Inflammatory and fibrotic mechanisms in the pathogenesis of left ventricular remodeling following myocardial infarction; cardiac aging.

Research Methods

Matrix metalloproteinase assays, in vivo myocardial injury models (myocardial infarction by coronary artery litigation), murine cardiovascular function analyses, two-dimensional gel electrophoresis, proteomics, histology, immunoblotting, fibroblast tissue culture, macrophage cell physiology assays.

Current Projects

  1. Identifying novel MMP substrates in post-MI tissues.
  2. Using omics strategies to identify novel extracellular matrix signaling pathways altered post-MI.
  3. Examining the roles of macrophages and fibroblasts in post-MI remodeling of the left ventricle.
  4. Determining the role of aging on the remodeling process.
  5. Discovering novel biomarkers of adverse left ventricular remodeling