Merry Lindsey, PhD

Areas of expertise

• General: Cardiovascular physiology, proteomics

• Specific: Inflammatory and fibrotic mechanisms in the pathogenesis of left ventricular remodeling following myocardial infarction, cardiac aging

Research methods

Matrix metalloproteinase assays, in vivo myocardial injury models (myocardial infarction by coronary artery litigation), murine cardiovascular function analyses, two-dimensional gel electrophoresis, proteomics, histology, immunoblotting, fibroblast tissue culture, macrophage cell physiology assays.

Current projects

• Identifying novel MMP substrates in post-MI tissues

• Using omics strategies to identify novel extracellular matrix signaling pathways altered post-MI

• Examining the roles of macrophages and fibroblasts in post-MI remodeling of the left ventricle

• Determining the role of aging on the remodeling process

• Discovering novel biomarkers of adverse left ventricular remodeling

For more information

• Biographical sketch
• Curriculum vitae
• Summary of research
• Links to PubMed articles