Faculty

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Béla Kanyicska, PhD

kanyicska, bela.jpgAssociate Professor
Office: N608
(601) 984-6917
Lab: N608; (601) 815-1285
Email: bkanyicska@umc.edu

Education

  • BA - Biology and chemistry, Eötvös Loránd University (ELTE), Budapest, Hungary, 1974
  • MS - Biochemistry, Eötvös Loránd University (ELTE), Budapest, Hungary, 1975
  • PhD - Neuroscience, Semmelweis University, Budapest, Hungary, 1999

Research interests

Hypothalamic neuronal circuitry is responsible for the integration of endocrine, autonomic and behavioral responses in order to ensure homeostasis of the organism. My research area lies in the "endocrine arm" of this vast and multifaceted regulatory system and it concerns with the regulation of hormone secretion of the anterior lobe of the pituitary gland. Specifically, my present research objective is to elucidate the intracellular signaling mechanisms by which endothelin-like peptides and dopamine affect pituitary hormone secretion and establish how steroid background influences the endothelin system in the pituitary gland and in the hypothalamus, respectively.

Current research topics

  • Cellular/molecular mechanisms by which long-term steroid (estradiol and/or progesterone) treatment affect the endothelin system in the pituitary gland and the central nervous system (various in vivo experimental models, real-time PCR, proteomics)
  • Modulation of GABA and glutamate neurotransmission in hypothalamus by endothelins (long-term neuron culture, patch-clamp recording, immunocytochemistry)
  • Systems level integration (modeling) of mechanistic information obtained at sub-cellular and single-cell levels to elucidate the regulation of neuroendocrine hypothalamic functions by endothelins and ovarian steroids