Glover, Sarah C., D.O.

Primary Practice Location:
University Hospital
2500 N. State St.
Jackson, MS 39216

Appointments: (888) 815-2005

Areas of Practice: Gastroenterology

Education

Board Certification:	Internal Medicine, Gastroenterology
Medical Education:	Chicago College of Osteopathic Medicine
Internship Program:	University Of Illinois At Chicago College Of Medicine
Residency Program:	University Of Illinois At Chicago College Of Medicine
Fellowship Program:	University of Florida College of Medicine
Fellowship Program:	University Of Illinois At Chicago College Of Medicine

Current Positions

Division Director , School of Medicine, Department of Medicine	01/2019 - Present
The University of Mississippi Medical Center Jackson, Mississippi 39216

Education

Midwestern University, DO, Doctor of Osteopathic Medicine	1998
Seattle Pacific University, BS, chemistry	1994

Specialty Certification Licensure

NPI
DEA, Practitioner, Drug Enforcement Administration	08/2017 - 09/2020
Licensure, Doctor of Osteopathic Medicine, Mississippi State Board of Medical Licensure	12/2018 - 06/2020
Certification, American Board of Internal Medicine	11/2004 - 04/2024

Academic Appointments or Other Previous Appointments

Associate Professor, University of Florida, School of Medicine, Department of Medicine	06/2013 - 01/2019
Assistant Professor, University of Florida, School of Medicine, Department of Medicine	2011 - 05/2013
Assistant Professor, University of Illinois at Chicago, School of Medicine, Department of Medicine	06/2004 - 12/2010

Honors, Awards, and Recognition

Category Award (Small Intestine) for Abstract Entitled: CD117+ Exosomes and Mast Cells From Hereditary Alpha Tryptasemia Patients Reveal Unique Phosphorylation, Lipidomics and Proteomics Profiles, American College of Gastroenterology	2018
Fellow, American Gastroenterological Association	2015
University of Illinois Hospital, Class Act Award	2009
Stem Cell Conference Travel Award, American Gastroenterological Association	2006
Loan Repayment Award, National Institutes of Health	2003
3rd Place, Fellow and Resident Research Competition, Chicago Society of Gastroenterology	2003

Professional Membership and Service

American Federation for Medical Research, Member	2019 - Present
Southern Society for Clinical Investigation, Member	2019 - Present
American Gastroenterological Association, Fellow	2015 - Present
Clinical Immunology Society, Member	2013 - Present
Federation of Clinical Immunology Societies, Member	2013 - Present
American College of Gastroenterology, Member	2013 - Present
Crohn's and Colitis Association of America, Member	2012 - Present
American Osteopathic Association, Member	2004 - Present

Committee Service

American Gastroenterological Association Research Scholar Award Review Panel 2020, Member	2020 - 2020
Small Business Innovation Research Grant Applications in Digestive sciences Special Emphasis Panel Study Section, Member	2020 - 2020

Community Service

Beit Lechem of Mississippi, Member

08/2019 - Present

Publications

Letter
Mendoza Alvarez LB, Barker R, Nelson C, DiMaggio T, Stone KD, Milner JD, Rosenthal JA, Petroni DH, Glover SC, Lyons JJ, Clinical response to omalizumab in patients with hereditary α-tryptasemia. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2020 Jan;124(1):99-100.e1	2020
Navaneethan U, Edminister T, Zhu X, Kommaraju K, Glover S, Vedolizumab Is Safe and Effective in Elderly Patients with Inflammatory Bowel Disease. Inflammatory bowel diseases, 2017 Apr;23(4):E17	2017
Li J, Shouval DS, Doty AL, Snapper SB, Glover SC, Increased Mucosal IL-22 Production of an IL-10RA Mutation Patient Following Anakin Treatment Suggests Further Mechanism for Mucosal Healing. Journal of clinical immunology, 2017 Feb;37(2):104-107	2017
Journal Article
Osterman MT, Gordon IO, Davis EM, Ciorba M, Glover SC, Abraham B, Khan F, Guo X, Yee EU, Allard FD, Claggett B, Shen B, Liu JJ, Mucosal Biomarker of Innate Immune Activation Predicts Response to Vedolizumab in Crohn's Disease. Inflammatory bowel diseases, 2020 Sep 18;26(10):1554-1561	2020
Mendoza Alvarez LB, Liu X, Glover S, Treatment-resistant eosinophilic oesophagitis successfully managed with tofacitinib. BMJ case reports, 2019 Dec 11;12(12)	2019
Danese S, Sandborn WJ, Colombel JF, Vermeire S, Glover SC, Rimola J, Siegelman J, Jones S, Bornstein JD, Feagan BG, Endoscopic, Radiologic, and Histologic Healing With Vedolizumab in Patients With Active Crohn's Disease. Gastroenterology, 2019 Oct;157(4):1007-1018.e7	2019
Chen C, Hartzema AG, Xiao H, Wei YJ, Chaudhry N, Ewelukwa O, Glover SC, Zimmermann EM, Real-world Pattern of Biologic Use in Patients With Inflammatory Bowel Disease: Treatment Persistence, Switching, and Importance of Concurrent Immunosuppressive Therapy. Inflammatory bowel diseases, 2019 Jul 17;25(8):1417-1427	2019
Ayoub F, Kamel AY, Ouni A, Chaudhry N, Ader Y, Tan S, Iqbal A, Zimmermann EM, Glover SC, Pre-operative total parenteral nutrition improves post-operative outcomes in a subset of Crohn's disease patients undergoing major abdominal surgery. Gastroenterology report, 2019 Apr;7(2):107-114	2019
Schwimmer D, Glover S, Primary Immunodeficiency and the Gut. Gastroenterology clinics of North America, 2019 Jun;48(2):199-220	2019
Glover SC, Nouri MZ, Tuna KM, Mendoza Alvarez LB, Ryan LK, Shirley JF, Tang Y, Denslow ND, Alli AA, Lipidomic analysis of urinary exosomes from hereditary α-tryptasemia patients and healthy volunteers. FASEB bioAdvances, 2019 Oct;1(10):624-638	2019
Sands BE, Sandborn WJ, Panaccione R, O'Brien CD, Zhang H, Johanns J, Adedokun OJ, Li K, Peyrin-Biroulet L, Van Assche G, Danese S, Targan S, Abreu MT, Hisamatsu T, Szapary P, Marano C, UNIFI Study Group., Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis. The New England journal of medicine, 2019 Sep 26;381(13):1201-1214	2019
Li J, Glover SC, Innate Lymphoid Cells in Inflammatory Bowel Disease. Archivum immunologiae et therapiae experimentalis, 2018 Dec;66(6):415-421	2018
Ewelukwa O, Perez R, Carter LE, Fernandez A, Glover S, Incorporation of Scribes Into the Inflammatory Bowel Disease Clinic Improves Quality of Care and Physician Productivity. Inflammatory bowel diseases, 2018 Feb 15;24(3):552-557	2018
Kamel AY, Ayoub F, Banerjee D, Chaudhry N, Ader Y, Tan S, Zimmermann EM, Glover SC, Iqbal A, Effects of Preoperative Use of Biologic Agents on Operative Outcomes in Crohn's Disease Patients. The American surgeon, 2018 Sep 1;84(9):1526-1530	2018
Shouval DS, Konnikova L, Griffith AE, Wall SM, Biswas A, Werner L, Nunberg M, Kammermeier J, Goettel JA, Anand R, Chen H, Weiss B, Li J, Loizides A, Yerushalmi B, Yanagi T, Beier R, Conklin LS, Ebens CL, Santos FGMS, Sherlock M, Goldsmith JD, Kotlarz D, Glover SC, Shah N, Bousvaros A, Uhlig HH, Muise AM, Klein C, Snapper SB, Enhanced TH17 Responses in Patients with IL10 Receptor Deficiency and Infantile-onset IBD. Inflammatory bowel diseases, 2017 Nov;23(11):1950-1961	2017
Westerveld D, Li J, Glover S, Oesophageal mastocytosis: eosinophilic oesophagitis without eosinophils? BMJ case reports, 2017 Aug 28;2017	2017
Westerveld D, Grajo J, Beattie L, Glover S, Vedolizumab: a novel medical intervention in the treatment of primary sclerosing cholangitis. BMJ case reports, 2017 May 13;2017	2017
Unnikrishnan A, Glover SC, Norkina O, Wingard JR, Norkin M, Complete resolution of severe ulcerative colitis after haploidentical hematopoietic stem cell transplantation followed by post-transplant high-dose cyclophosphamide. Bone marrow transplantation, 2017 Aug;52(8):1204-1205	2017
Li J, Doty AL, Tang Y, Berrie D, Iqbal A, Tan SA, Clare-Salzler MJ, Wallet SM, Glover SC, Enrichment of IL-17A⁺ IFN-γ⁺ and IL-22⁺ IFN-γ⁺ T cell subsets is associated with reduction of NKp44⁺ ILC3s in the terminal ileum of Crohn's disease patients. Clinical and experimental immunology, 2017 Oct;190(1):143-153	2017
Li J, Shouval DS, Doty AL, Snapper SB, Glover SC, Erratum to: Increased Mucosal IL-22 Production of an IL-10RA Mutation Patient Following Anakinra Treatment Suggests Further Mechanism for Mucosal Healing. Journal of clinical immunology, 2017 Feb;37(2):108	2017
Lyons JJ, Yu X, Hughes JD, Le QT, Jamil A, Bai Y, Ho N, Zhao M, Liu Y, O'Connell MP, Trivedi NN, Nelson C, DiMaggio T, Jones N, Matthews H, Lewis KL, Oler AJ, Carlson RJ, Arkwright PD, Hong C, Agama S, Wilson TM, Tucker S, Zhang Y, McElwee JJ, Pao M, Glover SC, Rothenberg ME, Hohman RJ, Stone KD, Caughey GH, Heller T, Metcalfe DD, Biesecker LG, Schwartz LB, Milner JD, Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number. Nature genetics, 2016 Dec;48(12):1564-1569	2016
Shouval DS, Biswas A, Kang YH, Griffith AE, Konnikova L, Mascanfroni ID, Redhu NS, Frei SM, Field M, Doty AL, Goldsmith JD, Bhan AK, Loizides A, Weiss B, Yerushalmi B, Yanagi T, Lui X, Quintana FJ, Muise AM, Klein C, Horwitz BH, Glover SC, Bousvaros A, Snapper SB, Interleukin 1β Mediates Intestinal Inflammation in Mice and Patients With Interleukin 10 Receptor Deficiency. Gastroenterology, 2016 Dec;151(6):1100-1104	2016
Nathoo S, Hood WA, Keihanian S, Collinsworth AL, Glover SC, Tofacitinib for the treatment of tumor necrosis factor-α inhibitor refractory esophageal Crohn's disease: a case report. Journal of medical case reports, 2016 Sep 23;10(1):264	2016
Westerveld D, Patel A, Drane W, Glover S, Coming full circle: an impressive case of Crohn's disease. BMJ case reports, 2016 Feb 17;2016	2016
Li J, Bharadwaj SS, Guzman G, Vishnubhotla R, Glover SC, ROCK I Has More Accurate Prognostic Value than MET in Predicting Patient Survival in Colorectal Cancer. Anticancer research, 2015 Jun;35(6):3267-73	2015
Coman RM, Glover SC, Gjymishka A, Febrile pleuropericarditis, a potentially life-threatening adverse event of balsalazide--case report and literature review of the side effects of 5-aminosalicylates. Expert review of clinical immunology, 2014 May;10(5):667-75	2014
Sandborn WJ, Feagan BG, Rutgeerts P, Hanauer S, Colombel JF, Sands BE, Lukas M, Fedorak RN, Lee S, Bressler B, Fox I, Rosario M, Sankoh S, Xu J, Stephens K, Milch C, Parikh A, GEMINI 2 Study Group., Vedolizumab as induction and maintenance therapy for Crohn's disease. The New England journal of medicine, 2013 Aug 22;369(8):711-21	2013
Feagan BG, Rutgeerts P, Sands BE, Hanauer S, Colombel JF, Sandborn WJ, Van Assche G, Axler J, Kim HJ, Danese S, Fox I, Milch C, Sankoh S, Wyant T, Xu J, Parikh A, GEMINI 1 Study Group., Vedolizumab as induction and maintenance therapy for ulcerative colitis. The New England journal of medicine, 2013 Aug 22;369(8):699-710	2013
Mahadevan U, Wolf DC, Dubinsky M, Cortot A, Lee SD, Siegel CA, Ullman T, Glover S, Valentine JF, Rubin DT, Miller J, Abreu MT, Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2013 Mar;11(3):286-92; quiz e24	2013
Rapier R, Huq J, Vishnubhotla R, Bulic M, Perrault CM, Metlushko V, Cho M, Tay RT, Glover SC, The extracellular matrix microtopography drives critical changes in cellular motility and Rho A activity in colon cancer cells. Cancer cell international, 2010 Jul 28;10:24	2010
Vishnubhotla R, Sun S, Huq J, Bulic M, Ramesh A, Guzman G, Cho M, Glover SC, ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging. Laboratory investigation; a journal of technical methods and pathology, 2007 Nov;87(11):1149-58	2007
Tang Y, Tan SA, Iqbal A, Li J, Glover SC, STAT3 Genotypic Variant rs744166 and Increased Tyrosine Phosphorylation of STAT3 in IL-23 Responsive Innate Lymphoid Cells during Pathogenesis of Crohn's Disease. Journal of immunology research, 2019;2019:9406146
Zhang D, Glover SC, Liu W, Liu X, Lai J, Small Bowel Pyogenic Granuloma With Cytomegalovirus Infection in a Patient With Crohn's Disease (Report of a Case and Review of the Literature). In vivo (Athens, Greece), 2019 Jan-Feb;33(1):251-254
Stoner PL, Kamel A, Ayoub F, Tan S, Iqbal A, Glover SC, Zimmermann EM, Perioperative Care of Patients with Inflammatory Bowel Disease: Focus on Nutritional Support. Gastroenterology research and practice, 2018;2018:7890161
Stewart DC, Berrie D, Li J, Liu X, Rickerson C, Mkoji D, Iqbal A, Tan S, Doty AL, Glover SC, Simmons CS, Quantitative assessment of intestinal stiffness and associations with fibrosis in human inflammatory bowel disease. PloS one, 2018;13(7):e0200377
Graves CL, Li J, LaPato M, Shapiro MR, Glover SC, Wallet MA, Wallet SM, Intestinal Epithelial Cell Regulation of Adaptive Immune Dysfunction in Human Type 1 Diabetes. Frontiers in immunology, 2016;7:679
Li J, Doty AL, Iqbal A, Glover SC, The differential frequency of Lineage(-)CRTH2(-)CD45(+)NKp44(-)CD117(-)CD127(+)ILC subset in the inflamed terminal ileum of patients with Crohn's disease. Cellular immunology, 2016 Jun-Jul;304-305:63-8
Li J, Doty A, Glover SC, Aryl hydrocarbon receptor signaling involves in the human intestinal ILC3/ILC1 conversion in the inflamed terminal ileum of Crohn's disease patients. Inflammation and cell signaling, 2016;3(3)
Yu HJ, Serebryannyy LA, Fry M, Greene M, Chernaya O, Hu WY, Chew TL, Mahmud N, Kadkol SS, Glover S, Prins G, Strakova Z, de Lanerolle P, Tumor stiffness is unrelated to myosin light chain phosphorylation in cancer cells. PloS one, 2013;8(11):e79776

Presentations

Poster Presentation, Features of Environmental Dust Exposure Induced Lung Disease Regulated by MyD88 Result in a Prolonged Adaptation Response, American Academy of Allergy, Asthma & Immunology (AAAAI), Philadelphia, PA	03/2020
Poster Presentation, E. COLI SEPSIS FOLLOWING FMT IN AN IGA DEFICIENT IBD SUBJECT, American College of Gastroenterology, San Antonio, Texas	11/2019
Poster Presentation, INCREASED MUCOSAL INNATE IMMUNE ACTIVATION IN HEREDITARY ALPHA TRYTPASEMIA SUBJECTS IS PREDICTIVE OF CLINICAL RESPONSE TO TOFACITANIB THERAPY, American College of Gastroenterology, San Antonio, TX	10/2019
Poster Presentation, REAL WORLD USE OF TACROLIMUS IN COMBINATION WITH BIOLOGICALS IS BENEFICIAL IN THE TREATMENT OF IBD, American College of Gastroenterology, San Antonio, Texas	10/2019
National and International Invited Seminars/Lectures, Ileal Biopsy Epithelial Cell Pyrotosis Predicts Clinical Response to Vedolizumab Therapy in Crohn’s Disease, Digestive Disease Week, San Diego, CA	05/2019
Poster Presentation, Identification of a Unique Population of GI Mast Cells in a Subset of Patients with Mast Cell Activation Syndrome, Digestive Disease Week, San Diego, CA	05/2019
Poster Presentation, Inhibition of Intestinal Epithelial Cell Pyroptosis and Associated Mucosal Barrier Defects is a Potential Therapeutic Mechanism of Action for Mesalamine in IBD, Digestive Disease Week, San Diego, CA	05/2019
Poster Presentation, Mast Cells in Patients with Hereditary α-Tryptasemia Promote HLA-DR Expression and a Th2-Polarizing Microenvironment in the Gastrointestinal Tract, American Association of Immunologists, San Diego, California	05/2019
Poster Presentation, Evaluating the impact of vedolizumab of postoperative complications in Inflammatory Bowel Disease Patients, American Society of Colon and Rectal Surgeons, Nashville, TN	05/2018
Poster Presentation, Predictors of 30 day readmission following major abdominal surgery for Crohn’s Disease, AMERICAN SOCIETY OF COLON AND RECTAL SURGEONS, Nashville, TN	05/2018

Directed Student Learning

Dissertation Committee Chair, Aberrant ILC Plasticity Contributes to Acute Campylobacteriosis and Chronic Intestinal Inflammation Advised: Ying Tang	2015 - 2019
Dissertation Committee Chair, ABERRANT INNATE IMMUNITY CONTRIBUTES TO DYSREGULATED ADAPTIVE IMMUNE RESPONSES IN PATIENTS WITH CROHN’ S DISEASE Advised: Jian Li	2012 - 2017
Dissertation Committee Chair, MECHANICAL MARKERS OF COLON CANCER A DIAGNOSTIC MODEL Advised: Shruthi Bharadwaj	2009 - 2013
Master's Thesis Committee Chair	2008 - 2010
Dissertation Committee Chair, The Role of ROCK in Colon Cancer Invasion Using Three-Dimensional Collagen I Microenvironments Advised: Ramana Vishnubhotla	2008 - 2012
Master's Thesis Committee Chair, Advised: Rebecca Mecum	2006 - 2008

Residency Training

Internal Medicine, Research Advisor	2019 - Present
Internal Medicine, Research Advisor	2014 - 06/2016

Fellows supervised

University of Florida, Research Advisor, 4 fellows supervised, Gastroenterology

08/2011 - 01/2020

Extramural, Clinical and Pre-Clinical Predictors of Response to Gattex in Short Bowel Syndrome, Takeda	01/2020 - 01/2022
Extramural, R21 DE028378-01A1 Innate Immune Mechanisms of Peridontal Disease in Inflammatory Bowel Disease, National Institute of Dental and Craniofacial Research	09/2019 - 08/2021
Extramural, A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of BMS-986165 in Subjects with Moderate-to-Severe Crohn's Disease, Bristol Myers Squibb	06/2019 - 05/2021
Extramural, R01DK073338 Role of Bacteria in Colitis-Associated Colon Cancer, National Institute of Diabetes and Digestive and Kidney	07/2018 - 01/2019
Extramural, R21 TR002639-01A1 Repurposing Pharmacological Agents for Inherited Mast Cell Disorders of the Gut	09/2017 - 06/2021
Extramural, Pfizer Pilot Research Award in Inflammatory Bowel Disease: Defective STAT3 Signaling in Inflammatory Bowel Disease, American Gastroenterological Association	07/2017 - 06/2018
Extramural, RO1 CA113975 PI Glover Role of Surface Roughness in Regulating Tumor Cell Behavior, National Cancer Institute	09/2008 - 06/2013
Extramural, T32 DK007788-03 Molecular Training in Gastroenterology and Heptaology, National Institute of Diabetes and Digestive Health	08/2000 - 06/2005

Glover, Sarah C., D.O.

Education

Current Positions

Education

Specialty Certification Licensure

Academic Appointments or Other Previous Appointments

Honors, Awards, and Recognition

Professional Membership and Service

Committee Service

Community Service

Sponsored Program Funding

Publications

Letter

Journal Article

Presentations

Directed Student Learning

Residency Training

Fellows supervised

Biography

Services & Procedures