Consider empiric choices above do not cover:
IDSA guidelines do not support longer courses of antibiotics, even for (previously recommended) non-glucose-fermenting gram-negative bacilli. There is some support for a 5-day course of antibiotics in the setting of rapid recovery/defervescence. *For any toxic patient, consider a Vancomycin loading dose of 25 mg/kg followed by 15 mg/kg every 12 hours. Every Vancomycin order requires pharmacokinetic consult.
**For patients who remain in septic shock/high risk of death, consider continuing two anti-pseudomonas agents for entire treatment course, regardless of sensitivities.