Center for Comparative Research

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Species Specific Procedures


Rodent caging: Investigators using rodents should note that the cage bottoms and wire bar lids used for housing mice and rats are different. For mice two sizes of cages are available and although large mouse and rat cages appear similar there are differences and the correct caging for the specific species is critical. Please consult with any of the CCR staff to be sure you are using the correct caging.

Rodent housing density: The number of rats or mice allowed per cage is based on the area of the cage floor and the weight of the animals. To prevent overcrowding investigators who are breeding animals or purchasing young animals are encouraged to monitor the weight of their animals as they grow and separate them when necessary. Individuals with breeding protocols should remember to house females individually as parturition approaches and that mice and rats should be weaned at 21 days of age to prevent overcrowding.

Nonhuman primates

Animal transportation: Nonhuman primates transported out of the CCR must be contained in a specialized filtered stainless steel cart. This "filtered cart" is designed to minimize the spread of potential allergens/diseases.

Employee health: Only authorized UMMC personnel should enter nonhuman primate rooms. All employees entering nonhuman primate areas must have a current, negative tuberculin skin test. Additionally, all personnel working with nonhuman primates must wear protective clothing according to Institutional Biosafety Committee requirements (eye protection, lab coats with long sleeves, face mask and gloves).

Quarantine: All newly received nonhuman primates are placed in quarantine in a negatively pressurized room for a minimum of six weeks. If no health problems are found, the primates are released to the investigator.