Developmental Origins of Diseases

High Birth Weight Babies

Although low birth weight increases the risk of death in early life and increases the risk of chronic disease in later life, high birth weight (8.8 pounds or greater for blacks and whites, 7.7 pounds or greater for Asians) is also a risk factor for chronic disease in later life.

Obesity prior to pregnancy or diabetes during pregnancy increases the risk for a high birth weight baby. High birth weight increases the risk for obesity by twofold in later life relative to individuals born with average birth weight. High birth weight babies also exhibit a greater risk to develop diabetes, and the risk of heart disease and cancer are also increased in those born too big.

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