Tariq Shafi, MD

Tariq Shafi, MD

Affiliate Faculty

Department:
SOM-Medicine

Email:
tshafi@umc.edu

Work Phone:
(601) 984-5687

Biography

Dr. Shafi is the John D. Bower Director of the Division of Nephrology and Professor of Medicine with a joint appointment in Physiology and Biophysics at the University of Mississippi Medical Center (UMMC). Dr. Shafi joined UMMC in December 2018 and is leading the growth of its clinical operations and shifting focus on clinical and translational research.

Dr. Shafi comes to UMMC with a wealth of accomplishments and experience. He received his medical degree from Dow Medical College in Karachi, Pakistan in 1990, followed by Internal Medicine residency training at Detroit’s Wayne State University. After several years in leadership roles at the Detroit Medical Center, Dr. Shafi pursued nephrology fellowship at Johns Hopkins Hospital and an MHS in Clinical Epidemiology at the Johns Hopkins School of Public Health. He then joined the Nephrology Division at Johns Hopkins University School of Medicine in 2008 and was a faculty member there until 2018.

Dr. Shafi is an NIH-funded clinician-scientist with a research focus on cardiovascular risk factors and outcomes in patients with kidney disease treated with dialysis. Dr. Shafi has extensive expertise in human subjects clinical research, biomarker studies, and health services research. Dr. Shafi is a permanent member of the NIH Health Services Organization and Delivery (HSOD) Study Section and is a member of the editorial boards of Clinical Journal of the American Society of Nephrology and the American Journal of Kidney Diseases.

Education

Dow Medical College, MBBS, Medicine1990

Specialty Certification Licensure

Certification, Nephrology

Academic Appointments or Other Previous Appointments

Division Director, School of Medicine, Department of Medicine

Sponsored Program Funding

Extramural, Simulation to Guide Implementation of Telemedicine Cardiorenal Interventions to Reduce Health Disparities, HRSA09/2019 - Present
Extramural, ESRD in the Medicare Population – AHRQ Technical Brief, AHRQ08/2018 - 11/2019
Extramural, Metabolomics of Uremic Symptoms in Dialysis Patients, NINR09/2017 - Present
Extramural, Cardiac Arrhythmia Monitoring and Related Outcomes, NHLBI12/2016 - Present

Publications

Letter

Titan S, Miao S, Tighiouart H, Chen N, Shi H, Zhang L, Li Z, Froissart M, Rossing P, Grubb A, Fan L, Mauer M, Bakoush O, Wyatt C, Shlipak MG, Shafi T, Inker LA, Levey AS, Performance of Indexed and Nonindexed Estimated GFR. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2020 Sep;76(3):446-4492020
Hu JR, Grams ME, Coresh J, Hwang S, Kovesdy CP, Guallar E, Rhee EP, Shafi T, Serum Metabolites and Cardiac Death in Patients on Hemodialysis. Clinical journal of the American Society of Nephrology : CJASN, 2019 May 7;14(5):747-7492019
Mullangi S, Sozio SM, Hellmann DB, Martire C, Lohani S, Segal P, Shafi T, Integrative Point-of-Care Ultrasound Curriculum to Impart Diagnostic Skills Relevant to Nephrology. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2019 Jun;73(6):894-8962019
Abraham AG, Shafi T, Tighiouart H, Moseley KF, Post WS, Inker LA, Coresh J, Shlipak MG, Levey AS, Effects of Body Size and Composition on Sex Differences in Measured GFR in a US Community-Based Older Cohort (MESA-Kidney). American journal of kidney diseases : the official journal of the National Kidney Foundation, 2018 Nov;72(5):767-7702018
Shafi T, Levey AS, Coresh J, In Reply to 'Plasma Clearance of Iohexol in Hemodialysis Patients Requires Prolonged Blood Sampling'. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016 May;67(5):811-22016
Shafi T, Pluznick JL, Renal Handling of β-Trace Protein: Interpreting the Evidence. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2015 Jun;65(6):9672015
Shafi T, Levey AS, Inker LA, Schwartz GJ, Knight C, Abraham AG, Eckfeldt JH, Coresh J, Plasma Iohexol Clearance for Assessing Residual Kidney Function in Dialysis Patients. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2015 Oct;66(4):728-302015
Dougherty JA, Young H, Shafi T, Serotonin syndrome induced by amitriptyline, meperidine, and venlafaxine. The Annals of pharmacotherapy, 2002 Oct;36(10):1647-82002

Journal Article

Toth-Manikowski SM, Sirich TL, Meyer TW, Hostetter TH, Hwang S, Plummer NS, Hai X, Coresh J, Powe NR, Shafi T, Contribution of 'clinically negligible' residual kidney function to clearance of uremic solutes. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2020 May 1;35(5):846-8532020
Chen Y, Zelnick LR, Wang K, Hoofnagle AN, Becker JO, Hsu CY, Feldman HI, Mehta RC, Lash JP, Waikar SS, Shafi T, Seliger SL, Shlipak MG, Rahman M, Kestenbaum BR, CRIC Study Investigators, Kidney Clearance of Secretory Solutes Is Associated with Progression of CKD: The CRIC Study. Journal of the American Society of Nephrology : JASN, 2020 Apr;31(4):817-8272020
Ku E, Yang W, McCulloch CE, Feldman HI, Go AS, Lash J, Bansal N, He J, Horwitz E, Ricardo AC, Shafi T, Sondheimer J, Townsend RR, Waikar SS, Hsu CY, CRIC Study Investigators, Race and Mortality in CKD and Dialysis: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2020 Mar;75(3):394-4032020
Gardezi AI, Karim MS, Rosenberg JE, Scialla JJ, Banerjee T, Powe NR, Shafi T, Parekh RS, Yevzlin AS, Astor BC, Markers of mineral metabolism and vascular access complications: The Choices for Healthy Outcomes in Caring for ESRD (CHOICE) study. Hemodialysis international. International Symposium on Home Hemodialysis, 2020 Jan;24(1):43-512020
Fan L, Steubl D, Inker LA, Tighiouart H, Simon AL, Foster MC, Karger AB, Eckfeldt JH, Li H, Tang J, He Y, Xie M, Xiong F, Li H, Zhang H, Hu J, Liao Y, Ye X, Shafi T, Chen W, Yu X, Levey AS, Estimating total small solute clearance in patients treated with continuous ambulatory peritoneal dialysis without urine and dialysate collection. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 2020 Jan;40(1):84-922020
O'Lone E, Viecelli AK, Craig JC, Tong A, Sautenet B, Herrington WG, Herzog CA, Jafar TH, Jardine M, Krane V, Levin A, Malyszko J, Rocco MV, Strippoli G, Tonelli M, Wang AYM, Wanner C, Zannad F, Winkelmayer WC, Wheeler DC, SONG-HD CVD Consensus Workshop Investigators, Establishing Core Cardiovascular Outcome Measures for Trials in Hemodialysis: Report of an International Consensus Workshop. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2020 Jul;76(1):109-1202020
Lamprea-Montealegre JA, Zelnick LR, Shlipak MG, Floyd JS, Anderson AH, He J, Christenson R, Seliger SL, Soliman EZ, Deo R, Ky B, Feldman HI, Kusek JW, deFilippi CR, Wolf MS, Shafi T, Go AS, Bansal N, CRIC Study Investigators, Cardiac Biomarkers and Risk of Atrial Fibrillation in Chronic Kidney Disease: The CRIC Study. Journal of the American Heart Association, 2019 Aug 6;8(15):e0122002019
Kaczmarski KR, Sozio SM, Chen J, Sang Y, Shafi T, Resistant hypertension and cardiovascular disease mortality in the US: results from the National Health and Nutrition Examination Survey (NHANES). BMC nephrology, 2019 Apr 25;20(1):1382019
Ma J, Karnovsky A, Afshinnia F, Wigginton J, Rader DJ, Natarajan L, Sharma K, Porter AC, Rahman M, He J, Hamm L, Shafi T, Gipson D, Gadegbeku C, Feldman H, Michailidis G, Pennathur S, Differential network enrichment analysis reveals novel lipid pathways in chronic kidney disease. Bioinformatics (Oxford, England), 2019 Sep 15;35(18):3441-34522019
Waikar SS, Srivastava A, Palsson R, Shafi T, Hsu CY, Sharma K, Lash JP, Chen J, He J, Lieske J, Xie D, Zhang X, Feldman HI, Curhan GC, Chronic Renal Insufficiency Cohort study investigators, Association of Urinary Oxalate Excretion With the Risk of Chronic Kidney Disease Progression. JAMA internal medicine, 2019 Apr 1;179(4):542-5512019
Coresh J, Inker LA, Sang Y, Chen J, Shafi T, Post WS, Shlipak MG, Ford L, Goodman K, Perichon R, Greene T, Levey AS, Metabolomic profiling to improve glomerular filtration rate estimation: a proof-of-concept study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2019 May 1;34(5):825-8332019
Hong YS, Ryu S, Chang Y, Caínzos-Achirica M, Kwon MJ, Zhao D, Shafi T, Lazo M, Pastor-Barriuso R, Shin H, Cho J, Guallar E, Hepatitis B virus infection and development of chronic kidney disease: a cohort study. BMC nephrology, 2018 Dec 11;19(1):3532018
Han Z, Xiao Z, Kalantar-Zadeh K, Moradi H, Shafi T, Waikar SS, Quarles LD, Yu Z, Tin A, Coresh J, Kovesdy CP, Validation of a Novel Modified Aptamer-Based Array Proteomic Platform in Patients with End-Stage Renal Disease. Diagnostics (Basel, Switzerland), 2018 Oct 8;8(4)2018
Shafi T, Guallar E, Mapping Progress in Reducing Cardiovascular Risk with Kidney Disease: Sudden Cardiac Death. Clinical journal of the American Society of Nephrology : CJASN, 2018 Sep 7;13(9):1429-14312018
Orlandi PF, Fujii N, Roy J, Chen HY, Lee Hamm L, Sondheimer JH, He J, Fischer MJ, Rincon-Choles H, Krishnan G, Townsend R, Shafi T, Hsu CY, Kusek JW, Daugirdas JT, Feldman HI, CRIC Study Investigators, Hematuria as a risk factor for progression of chronic kidney disease and death: findings from the Chronic Renal Insufficiency Cohort (CRIC) Study. BMC nephrology, 2018 Jun 26;19(1):1502018
Grams ME, Shafi T, Rhee EP, Metabolomics Research in Chronic Kidney Disease. Journal of the American Society of Nephrology : JASN, 2018 Jun;29(6):1588-15902018
Jang HR, Kang D, Sinn DH, Gu S, Cho SJ, Lee JE, Huh W, Paik SW, Ryu S, Chang Y, Shafi T, Lazo M, Guallar E, Cho J, Gwak GY, Nonalcoholic fatty liver disease accelerates kidney function decline in patients with chronic kidney disease: a cohort study. Scientific reports, 2018 Mar 16;8(1):47182018
Shafi T, Levey AS, Measurement and Estimation of Residual Kidney Function in Patients on Dialysis. Advances in chronic kidney disease, 2018 Jan;25(1):93-1042018
Mullangi S, Sozio SM, Segal P, Menez S, Martire C, Shafi T, Point-of-care ultrasound education to improve care of dialysis patients. Seminars in dialysis, 2018 Mar;31(2):154-1622018
Plantinga LC, King LM, Masud T, Shafi T, Burkart JM, Lea JP, Jaar BG, Burden and correlates of readmissions related to pulmonary edema in US hemodialysis patients: a cohort study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2018 Jul 1;33(7):1215-12232018
Jung M, Warren B, Grams M, Kwong YD, Shafi T, Coresh J, Rebholz CM, Selvin E, Performance of non-traditional hyperglycemia biomarkers by chronic kidney disease status in older adults with diabetes: Results from the Atherosclerosis Risk in Communities Study. Journal of diabetes, 2018 Apr;10(4):276-2852018
Inker LA, Levey AS, Tighiouart H, Shafi T, Eckfeldt JH, Johnson C, Okparavero A, Post WS, Coresh J, Shlipak MG, Performance of glomerular filtration rate estimating equations in a community-based sample of Blacks and Whites: the multiethnic study of atherosclerosis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2018 Mar 1;33(3):417-4252018
Hu JR, Coresh J, Inker LA, Levey AS, Zheng Z, Rebholz CM, Tin A, Appel LJ, Chen J, Sarnak MJ, Grams ME, Serum metabolites are associated with all-cause mortality in chronic kidney disease. Kidney international, 2018 Aug;94(2):381-3892018
Kim ED, Meoni LA, Jaar BG, Shafi T, Linda Kao WH, Estrella MM, Parekh R, Sozio SM, Association of Arterial Stiffness and Central Pressure With Cognitive Function in Incident Hemodialysis Patients: The PACE Study. Kidney international reports, 2017 Nov;2(6):1149-11592017
El Hage N, Jaar BG, Cheng A, Knight C, Blasco-Colmenares E, Gimenez L, Guallar E, Shafi T, Frequency of arrhythmia symptoms and acceptability of implantable cardiac monitors in Hemodialysis patients. BMC nephrology, 2017 Oct 10;18(1):3092017
Grams ME, Tin A, Rebholz CM, Shafi T, Köttgen A, Perrone RD, Sarnak MJ, Inker LA, Levey AS, Coresh J, Metabolomic Alterations Associated with Cause of CKD. Clinical journal of the American Society of Nephrology : CJASN, 2017 Nov 7;12(11):1787-17942017
Shafi T, Mullangi S, Jaar BG, Silber H, Autonomic dysfunction as a mechanism of intradialytic blood pressure instability. Seminars in dialysis, 2017 Nov;30(6):537-5442017
Toth-Manikowski SM, Mullangi S, Hwang S, Shafi T, Incremental short daily home hemodialysis: a case series. BMC nephrology, 2017 Jul 5;18(1):2162017
Foster MC, Levey AS, Inker LA, Shafi T, Fan L, Gudnason V, Katz R, Mitchell GF, Okparavero A, Palsson R, Post WS, Shlipak MG, Non-GFR Determinants of Low-Molecular-Weight Serum Protein Filtration Markers in the Elderly: AGES-Kidney and MESA-Kidney. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017 Sep;70(3):406-4142017
Kalantar-Zadeh K, Crowley ST, Beddhu S, Chen JLT, Daugirdas JT, Goldfarb DS, Jin A, Kovesdy CP, Leehey DJ, Moradi H, Navaneethan SD, Norris KC, Obi Y, O'Hare A, Shafi T, Streja E, Unruh ML, Vachharajani TJ, Weisbord S, Rhee CM, Renal Replacement Therapy and Incremental Hemodialysis for Veterans with Advanced Chronic Kidney Disease. Seminars in dialysis, 2017 May;30(3):251-2612017
Grams ME, Yang W, Rebholz CM, Wang X, Porter AC, Inker LA, Horwitz E, Sondheimer JH, Hamm LL, He J, Weir MR, Jaar BG, Shafi T, Appel LJ, Hsu CY, CRIC Study Investigators, Risks of Adverse Events in Advanced CKD: The Chronic Renal Insufficiency Cohort (CRIC) Study. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017 Sep;70(3):337-3462017
Perl J, Dember LM, Bargman JM, Browne T, Charytan DM, Flythe JE, Hickson LJ, Hung AM, Jadoul M, Lee TC, Meyer KB, Moradi H, Shafi T, Teitelbaum I, Wong LP, Chan CT, American Society of Nephrology Dialysis Advisory Group, The Use of a Multidimensional Measure of Dialysis Adequacy-Moving beyond Small Solute Kinetics. Clinical journal of the American Society of Nephrology : CJASN, 2017 May 8;12(5):839-8472017
Shafi T, Mullangi S, Toth-Manikowski SM, Hwang S, Michels WM, Residual Kidney Function: Implications in the Era of Personalized Medicine. Seminars in dialysis, 2017 May;30(3):241-2452017
Banerjee T, Meyer TW, Shafi T, Hostetter TH, Melamed M, Zhu Y, Powe NR, Free and total p-cresol sulfate levels and infectious hospitalizations in hemodialysis patients in CHOICE and HEMO. Medicine, 2017 Feb;96(6):e57992017
Shafi T, Sozio SM, Luly J, Bandeen-Roche KJ, St Peter WL, Ephraim PL, McDermott A, Herzog CA, Crews DC, Scialla JJ, Tangri N, Miskulin DC, Michels WM, Jaar BG, Zager PG, Meyer KB, Wu AW, Boulware LE, DEcIDE Network Patient Outcomes in End Stage Renal Disease Study Investigators, Antihypertensive medications and risk of death and hospitalizations in US hemodialysis patients: Evidence from a cohort study to inform hypertension treatment practices. Medicine, 2017 Feb;96(5):e59242017
Shafi T, Hostetter TH, Meyer TW, Hwang S, Hai X, Melamed ML, Banerjee T, Coresh J, Powe NR, Serum Asymmetric and Symmetric Dimethylarginine and Morbidity and Mortality in Hemodialysis Patients. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017 Jul;70(1):48-582017
Michels WM, Jaar BG, Ephraim PL, Liu Y, Miskulin DC, Tangri N, Crews DC, Scialla JJ, Shafi T, Sozio SM, Bandeen-Roche K, Cook CJ, Meyer KB, Boulware LE, DEcIDE Network Patient Outcomes in End Stage Renal Disease Study Investigators, Intravenous iron administration strategies and anemia management in hemodialysis patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2017 Jan 1;32(1):173-1812017
Shafi T, Powe NR, Meyer TW, Hwang S, Hai X, Melamed ML, Banerjee T, Coresh J, Hostetter TH, Trimethylamine N-Oxide and Cardiovascular Events in Hemodialysis Patients. Journal of the American Society of Nephrology : JASN, 2017 Jan;28(1):321-3312017
Shafi T, CKD to ESRD transition: does assessment of kidney function matter? Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2017 Jan 1;32(1):1-32017
Afshinnia F, Rajendiran TM, Karnovsky A, Soni T, Wang X, Xie D, Yang W, Shafi T, Weir MR, He J, Brecklin CS, Rhee EP, Schelling JR, Ojo A, Feldman H, Michailidis G, Pennathur S, Lipidomic Signature of Progression of Chronic Kidney Disease in the Chronic Renal Insufficiency Cohort. Kidney international reports, 2016 Nov;1(4):256-2682016
Meyer TW, Sirich TL, Fong KD, Plummer NS, Shafi T, Hwang S, Banerjee T, Zhu Y, Powe NR, Hai X, Hostetter TH, Kt/Vurea and Nonurea Small Solute Levels in the Hemodialysis Study. Journal of the American Society of Nephrology : JASN, 2016 Nov;27(11):3469-34782016
Shafi T, Michels WM, Levey AS, Inker LA, Dekker FW, Krediet RT, Hoekstra T, Schwartz GJ, Eckfeldt JH, Coresh J, Estimating residual kidney function in dialysis patients without urine collection. Kidney international, 2016 May;89(5):1099-11102016
Kruzan RM, Herzog CA, Wu A, Sang Y, Parekh RS, Matsushita K, Hwang S, Cheng A, Coresh J, Powe NR, Shafi T, Association of NTproBNP and cTnI with outpatient sudden cardiac death in hemodialysis patients: the Choices for Healthy Outcomes in Caring for ESRD (CHOICE) study. BMC nephrology, 2016 Feb 20;17:182016
Inker LA, Tighiouart H, Coresh J, Foster MC, Anderson AH, Beck GJ, Contreras G, Greene T, Karger AB, Kusek JW, Lash J, Lewis J, Schelling JR, Navaneethan SD, Sondheimer J, Shafi T, Levey AS, GFR Estimation Using β-Trace Protein and β2-Microglobulin in CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016 Jan;67(1):40-82016
Winters KD, Toth-Manikowski S, Martire C, Shafi T, Hand-carried ultrasound use in clinical nephrology: Case report. Medicine, 2016 Jul;95(30):e41662016
Camacho O, Rosales MC, Shafi T, Fullman J, Plummer NS, Meyer TW, Sirich TL, Effect of a sustained difference in hemodialytic clearance on the plasma levels of p-cresol sulfate and indoxyl sulfate. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2016 Aug;31(8):1335-412016
Inker LA, Shafi T, Okparavero A, Tighiouart H, Eckfeldt JH, Katz R, Johnson WC, Dermond N, Tariq Z, Benayache I, Post WS, Coresh J, Levey AS, Shlipak MG, Effects of Race and Sex on Measured GFR: The Multi-Ethnic Study of Atherosclerosis. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016 Nov;68(5):743-7512016
Parekh RS, Meoni LA, Jaar BG, Sozio SM, Shafi T, Tomaselli GF, Lima JA, Tereshchenko LG, Estrella MM, Kao WH, Rationale and design for the Predictors of Arrhythmic and Cardiovascular Risk in End Stage Renal Disease (PACE) study. BMC nephrology, 2015 Apr 24;16:632015
Tangri N, Miskulin DC, Zhou J, Bandeen-Roche K, Michels WM, Ephraim PL, McDermott A, Crews DC, Scialla JJ, Sozio SM, Shafi T, Jaar BG, Meyer K, Boulware LE, DEcIDE Network Patient Outcomes in End-Stage Renal Disease Study Investigators, Effect of intravenous iron use on hospitalizations in patients undergoing hemodialysis: a comparative effectiveness analysis from the DEcIDE-ESRD study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2015 Apr;30(4):667-752015
Galiatsatos P, Parakh K, Monti J, Thavarajah S, Aneke-Ogbu H, Watson A, Kim D, Wang NY, Shafi T, Silber HA, A finger photoplethysmography waveform during the valsalva maneuver detects changes in left heart filling pressure after hemodialysis. BMC nephrology, 2015 Aug 14;16:1382015
Kim ED, Sozio SM, Estrella MM, Jaar BG, Shafi T, Meoni LA, Kao WH, Lima JA, Parekh RS, Cross-sectional association of volume, blood pressures, and aortic stiffness with left ventricular mass in incident hemodialysis patients: the Predictors of Arrhythmic and Cardiovascular Risk in End-Stage Renal Disease (PACE) study. BMC nephrology, 2015 Aug 7;16:1312015
Chang A, Greene TH, Wang X, Kendrick C, Kramer H, Wright J, Astor B, Shafi T, Toto R, Lewis J, Appel LJ, Grams M, The effects of weight change on glomerular filtration rate. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2015 Nov;30(11):1870-72015
Shafi T, Waheed S, Zager PG, Hypertension in hemodialysis patients: an opinion-based update. Seminars in dialysis, 2014 Mar;27(2):146-532014
Crews DC, Scialla JJ, Liu J, Guo H, Bandeen-Roche K, Ephraim PL, Jaar BG, Sozio SM, Miskulin DC, Tangri N, Shafi T, Meyer KB, Wu AW, Powe NR, Boulware LE, Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) Patient Outcomes in End Stage Renal Disease Study Investigators, Predialysis health, dialysis timing, and outcomes among older United States adults. Journal of the American Society of Nephrology : JASN, 2014 Feb;25(2):370-92014
Chatterjee R, Brancati FL, Shafi T, Edelman D, Pankow JS, Mosley TH, Selvin E, Yeh HC, Non-traditional risk factors are important contributors to the racial disparity in diabetes risk: the atherosclerosis risk in communities study. Journal of general internal medicine, 2014 Feb;29(2):290-72014
Jaar BG, Zhang L, Chembrovich SV, Sozio SM, Shafi T, Scialla JJ, Tomaselli GF, Lima JA, Kao WH, Parekh RS, Meoni LA, Incidental findings on cardiac computed tomography in incident hemodialysis patients: the predictors of arrhythmic and cardiovascular events in end-stage renal disease (PACE) study. BMC nephrology, 2014 May 1;15:682014
Shafi T, Zager PG, Sozio SM, Grams ME, Jaar BG, Christenson RH, Boulware LE, Parekh RS, Powe NR, Coresh J, Troponin I and NT-proBNP and the association of systolic blood pressure with outcomes in incident hemodialysis patients: the Choices for Healthy Outcomes in Caring for ESRD (CHOICE) Study. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014 Sep;64(3):443-512014
Crews DC, Scialla JJ, Boulware LE, Navaneethan SD, Nally JV Jr, Liu X, Arrigain S, Schold JD, Ephraim PL, Jolly SE, Sozio SM, Michels WM, Miskulin DC, Tangri N, Shafi T, Wu AW, Bandeen-Roche K, DEcIDE Network Patient Outcomes in End Stage Renal Disease Study Investigators, Comparative effectiveness of early versus conventional timing of dialysis initiation in advanced CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014 May;63(5):806-152014
Scialla JJ, Kao WH, Crainiceanu C, Sozio SM, Oberai PC, Shafi T, Coresh J, Powe NR, Plantinga LC, Jaar BG, Parekh RS, Biomarkers of vascular calcification and mortality in patients with ESRD. Clinical journal of the American Society of Nephrology : CJASN, 2014 Apr;9(4):745-552014
Shafi T, Sozio SM, Bandeen-Roche KJ, Ephraim PL, Luly JR, St Peter WL, McDermott A, Scialla JJ, Crews DC, Tangri N, Miskulin DC, Michels WM, Jaar BG, Herzog CA, Zager PG, Meyer KB, Wu AW, Boulware LE, DEcIDE Network Patient Outcomes in End Stage Renal Disease Study Investigators, Predialysis systolic BP variability and outcomes in hemodialysis patients. Journal of the American Society of Nephrology : JASN, 2014 Apr;25(4):799-8092014
Miskulin DC, Tangri N, Bandeen-Roche K, Zhou J, McDermott A, Meyer KB, Ephraim PL, Michels WM, Jaar BG, Crews DC, Scialla JJ, Sozio SM, Shafi T, Wu AW, Cook C, Boulware LE, Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) Network Patient Outcomes in End Stage Renal Disease Study Investigators, Intravenous iron exposure and mortality in patients on hemodialysis. Clinical journal of the American Society of Nephrology : CJASN, 2014 Nov 7;9(11):1930-92014
Banerjee T, Kim SJ, Astor B, Shafi T, Coresh J, Powe NR, Vascular access type, inflammatory markers, and mortality in incident hemodialysis patients: the Choices for Healthy Outcomes in Caring for End-Stage Renal Disease (CHOICE) Study. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014 Dec;64(6):954-612014
Scialla JJ, Liu J, Crews DC, Guo H, Bandeen-Roche K, Ephraim PL, Tangri N, Sozio SM, Shafi T, Miskulin DC, Michels WM, Jaar BG, Wu AW, Powe NR, Boulware LE, DEcIDE Network Patient Outcomes in End Stage Renal Disease Study Investigators, An instrumental variable approach finds no associated harm or benefit with early dialysis initiation in the United States. Kidney international, 2014 Oct;86(4):798-8092014
Melamed ML, Plantinga L, Shafi T, Parekh R, Meyer TW, Hostetter TH, Coresh J, Powe NR, Retained organic solutes, patient characteristics and all-cause and cardiovascular mortality in hemodialysis: results from the retained organic solutes and clinical outcomes (ROSCO) investigators. BMC nephrology, 2013 Jun 27;14:1342013
Flythe JE, Inrig JK, Shafi T, Chang TI, Cape K, Dinesh K, Kunaparaju S, Brunelli SM, Association of intradialytic blood pressure variability with increased all-cause and cardiovascular mortality in patients treated with long-term hemodialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2013 Jun;61(6):966-742013
Shafi T, Sozio SM, Plantinga LC, Jaar BG, Kim ET, Parekh RS, Steffes MW, Powe NR, Coresh J, Selvin E, Serum fructosamine and glycated albumin and risk of mortality and clinical outcomes in hemodialysis patients. Diabetes care, 2013 Jun;36(6):1522-332013
St Peter WL, Sozio SM, Shafi T, Ephraim PL, Luly J, McDermott A, Bandeen-Roche K, Meyer KB, Crews DC, Scialla JJ, Miskulin DC, Tangri N, Jaar BG, Michels WM, Wu AW, Boulware LE, DEcIDE Network Patient Outcomes in End-Stage Renal Disease Study Investigators, Patterns in blood pressure medication use in US incident dialysis patients over the first 6 months. BMC nephrology, 2013 Nov 12;14:2492013
Shafi T, Matsushita K, Selvin E, Sang Y, Astor BC, Inker LA, Coresh J, Comparing the association of GFR estimated by the CKD-EPI and MDRD study equations and mortality: the third national health and nutrition examination survey (NHANES III). BMC nephrology, 2012 Jun 15;13:422012
Astor BC, Shafi T, Hoogeveen RC, Matsushita K, Ballantyne CM, Inker LA, Coresh J, Novel markers of kidney function as predictors of ESRD, cardiovascular disease, and mortality in the general population. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2012 May;59(5):653-622012
Boulware LE, Tangri N, Ephraim PL, Scialla JJ, Sozio SM, Crews DC, Shafi T, Miskulin DC, Liu J, St Peter W, Jaar BG, Wu AW, Powe NR, Navaneethan SD, Bandeen-Roche K, DEcIDE ESRD Patient Outcomes in Renal Disease Study Investigators, Comparative effectiveness studies to improve clinical outcomes in end stage renal disease: the DEcIDE patient outcomes in end stage renal disease study. BMC nephrology, 2012 Dec 6;13:1672012
Shafi T, Parekh RS, Jaar BG, Plantinga LC, Oberai PC, Eckfeldt JH, Levey AS, Powe NR, Coresh J, Serum β-trace protein and risk of mortality in incident hemodialysis patients. Clinical journal of the American Society of Nephrology : CJASN, 2012 Sep;7(9):1435-452012
Geetha D, Parkhie S, Nadkarni GN, He C, Shafi T, Polyomavirus-associated nephropathy: a comparison of 2 different strategies for immunosuppression reduction. Medicine, 2011 Sep;90(5):296-3022011
Shafi T, Choi MJ, Racusen LC, Spacek LA, Berry C, Atta M, Fine DM, Ritonavir-induced acute kidney injury: kidney biopsy findings and review of literature. Clinical nephrology, 2011 Feb;75 Suppl 1(0 1):60-42011
Chatterjee R, Yeh HC, Shafi T, Selvin E, Anderson C, Pankow JS, Miller E, Brancati F, Serum and dietary potassium and risk of incident type 2 diabetes mellitus: The Atherosclerosis Risk in Communities (ARIC) study. Archives of internal medicine, 2010 Oct 25;170(19):1745-512010
Shafi T, Jaar BG, Plantinga LC, Fink NE, Sadler JH, Parekh RS, Powe NR, Coresh J, Association of residual urine output with mortality, quality of life, and inflammation in incident hemodialysis patients: the Choices for Healthy Outcomes in Caring for End-Stage Renal Disease (CHOICE) Study. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2010 Aug;56(2):348-582010
Shafi T, Appel LJ, Miller ER 3rd, Klag MJ, Parekh RS, Changes in serum potassium mediate thiazide-induced diabetes. Hypertension (Dallas, Tex. : 1979), 2008 Dec;52(6):1022-92008
Flack JM, Peters R, Shafi T, Alrefai H, Nasser SA, Crook E, Prevention of hypertension and its complications: theoretical basis and guidelines for treatment. Journal of the American Society of Nephrology : JASN, 2003 Jul;14(7 Suppl 2):S92-82003
Hopper JA, Shafi T, Management of the hospitalized injection drug user. Infectious disease clinics of North America, 2002 Sep;16(3):571-872002
Shafi T, Hussain T, Quraishy MS, The blue rubber bleb syndrome. JPMA. The Journal of the Pakistan Medical Association, 1993 Jan;43(1):20-11993
Brown SB, Hatzikonstantinou H, Herries DG, The role of peroxide in haem degradation. A study of the oxidation of ferrihaems by hydrogen peroxide. The Biochemical journal, 1978 Sep 15;174(3):901-71978
Hishida M, Shafi T, Appel LJ, Maruyama S, Inaguma D, Matsushita K, Lower levels of proteinuria are associated with elevated mortality in incident dialysis patients. PloS one, 2019;14(12):e0226866
Ruilope LM, Agarwal R, Anker SD, Bakris GL, Filippatos G, Nowack C, Kolkhof P, Joseph A, Mentenich N, Pitt B, FIGARO-DKD study investigators, Design and Baseline Characteristics of the Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease Trial. American journal of nephrology, 2019;50(5):345-356
Bakris GL, Agarwal R, Anker SD, Pitt B, Ruilope LM, Nowack C, Kolkhof P, Ferreira AC, Schloemer P, Filippatos G, on behalf of the FIDELIO-DKD study investigators, FIDELIO-DKD study investigators, Design and Baseline Characteristics of the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease Trial. American journal of nephrology, 2019;50(5):333-344
Bryant TS, Duggal P, Yu B, Morrison AC, Shafi T, Ehret G, Franceschini N, Boerwinkle E, Coresh J, Tin A, Association of FMO3 Variants with Blood Pressure in the Atherosclerosis Risk in Communities Study. International journal of hypertension, 2019;2019:2137629
Lyu B, Banerjee T, Scialla JJ, Shafi T, Yevzlin AS, Powe NR, Parekh RS, Astor BC, Vascular Calcification Markers and Hemodialysis Vascular Access Complications. American journal of nephrology, 2018;48(5):330-338
Warsame F, Ying H, Haugen CE, Thomas AG, Crews DC, Shafi T, Jaar B, Chu NM, Segev DL, McAdams-DeMarco MA, Intradialytic Activities and Health-Related Quality of Life Among Hemodialysis Patients. American journal of nephrology, 2018;48(3):181-189
Shafi T, Hypertensive urgencies and emergencies. Ethnicity & disease, 2004 Autumn;14(4):S2-32-7
Scialla JJ, Parekh RS, Eustace JA, Astor BC, Plantinga L, Jaar BG, Shafi T, Coresh J, Powe NR, Melamed ML, Race, Mineral Homeostasis and Mortality in Patients with End-Stage Renal Disease on Dialysis. American journal of nephrology, 2015;42(1):25-34
Shafi T, Meyer TW, Hostetter TH, Melamed ML, Parekh RS, Hwang S, Banerjee T, Coresh J, Powe NR, Free Levels of Selected Organic Solutes and Cardiovascular Morbidity and Mortality in Hemodialysis Patients: Results from the Retained Organic Solutes and Clinical Outcomes (ROSCO) Investigators. PloS one, 2015;10(5):e0126048

Clinical Trial

Shafi T, Sirich TL, Meyer TW, Hostetter TH, Plummer NS, Hwang S, Melamed ML, Banerjee T, Coresh J, Powe NR, Results of the HEMO Study suggest that p-cresol sulfate and indoxyl sulfate are not associated with cardiovascular outcomes. Kidney international, 2017 Dec;92(6):1484-14922017
Miskulin DC, Zhou J, Tangri N, Bandeen-Roche K, Cook C, Ephraim PL, Crews DC, Scialla JJ, Sozio SM, Shafi T, Jaar BG, Boulware LE, DEcIDE Network Patient Outcomes in End Stage Renal Disease Study Investigators, Trends in anemia management in US hemodialysis patients 2004-2010. BMC nephrology, 2013 Dec 1;14:2642013
Chatterjee R, Yeh HC, Shafi T, Anderson C, Pankow JS, Miller ER, Levine D, Selvin E, Brancati FL, Serum potassium and the racial disparity in diabetes risk: the Atherosclerosis Risk in Communities (ARIC) Study. The American journal of clinical nutrition, 2011 May;93(5):1087-912011
Mokwe E, Ohmit SE, Nasser SA, Shafi T, Saunders E, Crook E, Dudley A, Flack JM, Determinants of blood pressure response to quinapril in black and white hypertensive patients: the Quinapril Titration Interval Management Evaluation trial. Hypertension (Dallas, Tex. : 1979), 2004 Jun;43(6):1202-72004

Comment

Shafi T, Hospitalist care. Annals of internal medicine, 2003 Oct 21;139(8):7032003

Editorial

Menez S, Hanouneh M, Shafi T, Jaar BG, Indoxyl sulfate is associated with mortality after AKI - more evidence needed! BMC nephrology, 2019 Jul 26;20(1):2802019
Shafi T, Jaar BG, Maintaining Patients on Home Hemodialysis: The Journey Matters as Does the Destination. Clinical journal of the American Society of Nephrology : CJASN, 2017 Aug 7;12(8):1209-12112017
Toth-Manikowski SM, Shafi T, Hemodialysis Prescription for Incident Patients: Twice Seems Nice, But Is It Incremental? American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016 Aug;68(2):180-1832016

Presentations

National and International Invited Seminars/Lectures, 03/2020 “GlomCon Conference on COVID19 in CKD/ESRD” Expert discussant. Online/Worldwide. https://glomcon.org/covid-19/covid19-in-ckd-esrd-patient-population/
National and International Invited Seminars/Lectures, 05/2019 “Role of Implantable Cardiac Monitors in Dialysis Patients”, National Kidney Foundation 2019 Spring Clinical Meeting, Boston, MA
National and International Invited Seminars/Lectures, 01/2019 “Sudden Cardiac Death in Dialysis Patients: You Can’t Treat What You Don’t Know” Nephrology Grand Rounds, University of Tennessee, Memphis, TN
National and International Invited Seminars/Lectures, 10/2018 “How Much is Enough: Assessing Patient Response to Ultrafiltration and Developing Quality Metrics”, American Society of Nephrology 2018 Kidney Week, San Diego, CA
National and International Invited Seminars/Lectures, 10/2018 “Diabetes and Late-Stage CKD: Challenges and Opportunities”, Nephrology Grand Rounds, Johns Hopkins University, Baltimore, MD
National and International Invited Seminars/Lectures, 05/2018 “Integrating Diagnostic Point of Care Ultrasound in Nephrology Training”, American Society of Nephrology, Training Program Director Retreat, Chicago, IL
National and International Invited Seminars/Lectures, 04/2018 “Incremental Dialysis”, CKD Conference, Hershey Medical Center, Hershey, PA
National and International Invited Seminars/Lectures, 03/2018 “Sudden Cardiac Death in Dialysis Patients: You Can’t Treat What You Don’t Know” Medicine Grand Rounds, George Washington University, Washington, DC
National and International Invited Seminars/Lectures, 10/2017 “Chronic Kidney Disease: An Update” Ngyuen Tri Phong Hospital, Saigon, Vietnam
National and International Invited Seminars/Lectures, 10/2017 “β-Trace Protein: GFR Estimation and Risk Prediction” Siemens Healthineers Middle East Science & Innovation Days. Dubai, UAE
National and International Invited Seminars/Lectures, 06/2016 “Wading Through a Sea of Numbers: Managing Hypertension in Dialysis Patients” The 61st Annual Meeting of the Japanese Society for Dialysis Therapy, Osaka, Japan
National and International Invited Seminars/Lectures, 12/2015 “From Uremic Frost to Gold Dust: Searching for the Elusive Toxins in an Evidence Desert” Renal Grand Rounds, University of Maryland, Baltimore, MD
National and International Invited Seminars/Lectures, 06/2015 “β-Trace Protein for Estimating Residual Kidney Function in Dialysis Patients” International Federation for Clinical Chemistry 2015 Annual Meeting, Paris, France.
National and International Invited Seminars/Lectures, 04/2015 “Kidney Markers for Cardiovascular Risk Assessment” Siemens 4th Plasma Protein Scientific Days, Marburg, Germany
National and International Invited Seminars/Lectures, 02/2015 “Squeezing Water from a Stone: Residual Kidney Function in Dialysis Patients” Nephrology Research Conference. Tufts Medical Center, Boston, MA
National and International Invited Seminars/Lectures, 09/2014 “The World’s Renal Registries; New Information from US Renal Data System 2013 and Beyond” International Society of Blood Purification and Therapeutic Apheresis Academy 2014 Joint Conference. National Harbor, MD
National and International Invited Seminars/Lectures, 05/2013 “Comparative Effectiveness of Antihypertensive Medications in Dialysis Patients” The DECIDE ESRD Study. University of Leiden, The Netherlands

Honors, Awards, and Recognition

2020: Elected, Fellow of the Southern Society of Clinical Investigation
2017: Nominated to participate in leadership program: Leading Transformations in Value-Based Health Care at Johns Hopkins Bloomberg School of Public Health
2013: Selected to participate in Johns Hopkins Junior Faculty Leadership Skills Program
2011: Top Young Investigator Oral Abstract for the category “Dialysis”. American Society of Nephrology Kidney Week 2011 Annual Meeting, November 10-13 in Philadelphia, PA
2008: Third Prize, Third Annual Young Investigator Forum, National Kidney Foundation 2008 Spring Clinical Meeting, Dallas, TX
2007: First Prize, Third Annual Post-doctoral Fellows Poster Competition, Bloomberg School of Public Health
2001: Paul E. Ruble Award for Teaching Excellence. Wayne State University, Detroit, Michigan