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  • Andrew D. Smith, MD, PhD

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    Associate Professor
    Director, Radiology Research
    Body and Oncologic Radiologist
    Phone: (601) 815-5615
    Fax: (601) 984-4986


    Clinical practice

    • General radiology
    • Body imaging
    • PET CT imaging


    • Doctor of Philosophy – Molecular & Cellular Biology
          Dissertation – “Recombinant AAV [viral] gene therapy in lung cells”
          Molecular Pathogenesis of Cancer Program Member
          Medical College of Ohio. Toledo, Ohio

    Medical school

    • Medical College of Ohio, Toledo, OH
    • PhD, Medical College of Ohio, Toledo, OH


    • Riverside Methodist Hospital, Columbus, OH


    • Diagnostic Radiology, Cleveland Clinic, Cleveland, OH


    • Abdominal Imaging, Cleveland Clinic, Cleveland, OH

    Board certification

    • American Board of Radiology

    Areas of interest

    Clinical interests

    • Primary and metastatic
    • Kidney cancer
    • Tumor response evaluation
    • Cirrhosis

    Research interests

    • Non-invasive methods for screening, diagnosis and response evaluation in chronic liver disease and cirrhosis using liver surface nodularity quantification on CT and MRI [patent pending]
    • Advanced CT post-processing methods for improving accuracy, inter-observer agreement and reader confidence in diagnosing ischemic strokes by noncontract CT and CTA [patent pending]
    • Advanced CT post-processing methods for near instant diagnosis of osteoporosis and osteopenia on routine CT images of the chest, abdomen, or pelvis. [Patent pending]
    • CT imaging findings that predict survival and quality of life in patients with metastatic renal cell carcinoma and metastatic melanoma treated with anti-angiogenic targeted therapy. [Patent pending; Pfizer grant]
    • Multi-institutional chart, coding, billing study to evaluate outcomes, complications and costs associated with the management of Bosniak cystic renal lesions (category iif, iii & iv)

    Research publications

    • Docarmo JM, da Silva AA, Moak SP, Houghton H, Smith AD, Reckelhoff JF, Hall J. Regulation of blood pressure, appetite, and glucose by edogenous melanocortin system in hyperandrogenemic female SHR. American Journal of Hypertension 2015: Accepted and in press.
    • Smith AD, Branch C, Zand K, Thaggard K, Hosch R, Subramony C, Zhang H, Bryan J, Vasanji A, Griswold M, Xu Z. Liver surface nodularity quantification from computed tomography images as a biomarker for detection and evaluation of cirrhosis.Radiology 2015: Accepted an in press
    • Grignol V, Smith AD, Shlapak D, Zhang X, Martin Del Campo S, Carson WE. Increased visceral to subcutaneous fat ratio is associated with decreased overall survival in patients with metastatic melanoma receiving anti-angiogenic therapy. J Surg Onc 2015; Accepted and in press.
    • Cui D, Lynch JD, Smith AD, Wilson TD, Lehman MN. Stereoscopic vascular models of the head and neck: a computed tomography angiography visualization. Anat Sci Educ. 2015: Accepted an in press.
    • Smith AD, Gray MR, Martin del Campo S, Shlapak D, Ganeshan B, Zhang X, Zhang H, Carson WE. Predicting overall survival in patients with metastatic melanoma on anti-angiogenic therapy and RECIST Stable Disease on initial post-therapy images using CT texture analysis. Am J Roentgenol. 2015; 205:W283-W293.
    • Smith AD, Allen BC, Sanyal R, Carson JD, Zhang H, Williams JH, Collins C, Griswold M, Zhang X. Outcomes, complications and costs in the management of Bosniak cystic renal lesions. Am J Roentgenol. 2015; 204:W550-6.
    • Maranon RO, Lima R, Spradley FT, co Carmo JM, Zhang H, Smith AD, Bui E, Thomas L, Moulana M, Hall JE, Granger JP, Reckelhoff JF. Roles for the sympathetic nervous system, renal nerves, and CNS melanocortin-4 receptor in the elevated blood pressure in hyperandrogenemic female rats. Amer J Physiol Regul Integr Comp Phyiol. 2015; 308:R708-13.
    • Souza FF, Smith AD, Araujo C, Jagannathan J, Johnston C, ORegan K, Shinagare A, Ramaiya N. New targeted molecular therapies for cancer: radiological response to intrathoracic malignancies and cardiopulmonary toxicity: what the radiologist needs to know. 2014. Cancer Imaging. 14:26.