Surgical techniques such as: Rat and mouse model of placental ischemia (reduced uterine perfusion pressure), chronic infusions via implantation of mini-osmotic pumps. Molecular techniques such as: Western blot, ELISA, histology, vessel transfections, etc. Acute measurement of arterial blood pressure via catheter, Ex-vivo measurement of cerebrovascular function, cerebral blood flow autoregulation.
Mechanisms for placental ischemia mediated cerebrovascular abnormalities
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