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  • Merry L. Lindsey, PhD

    Lindsey, Merry 100X150

    Professor of Physiology and Medicine
    Director, Mississippi Center for Heart Research
    Office: G351-04
    Lab: G364/74
    (601) 815-1329
    Lab: (601) 984-1824

    Areas of expertise

    • General: Cardiovascular physiology, proteomics
    • Specific: Inflammatory and fibrotic mechanisms in the pathogenesis of left ventricular remodeling following myocardial infarction; cardiac aging.

    Research methods

    Matrix metalloproteinase assays, in vivo myocardial injury models (myocardial infarction and transverse aortic constriction models), murine cardiovascular function analyses, two-dimensional gel electrophoresis, proteomics, histology, immunoblotting, fibroblast tissue culture, macrophage functional assays

    Current projects

    1. Identifying novel MMP-7 and MMP-9 substrates in post-MI tissues.
    2. Using peptidomics to identify novel extracellular matrix signaling pathways altered post-MI.
    3. Examining the roles of macrophages and fibroblasts in post-MI remodeling of the left ventricle.
    4. Determining the role of aging or periodontal disease on the remodeling process.
    5. Discovering novel biomarkers of adverse left ventricular remodeling.