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  • Complement Hemolytic Activity, Total (CH50)

    Test Name:Complement Hemolytic Activity, Total (CH50)
    Epic Order Code:LAB154
    CPT Code:86162
    Specimen(s) Type:Serum; 1.0 mL
    Acceptable Container(s):
    Testing Schedule:Monday - Friday
    Turn Around Time:STAT: NA  
     Routine: 1 - 3 days
    Collection Information:No special patient preparation is required. Obtain specimen by standard collection procedures.
    Transport Information:Deliver to lab immediately. All specimens must be signed into the laboratory.
    Reference Clients:If unable to deliver to the lab immediately, centrifuge the specimen and remove serum from the red cells within 1 hour. Freeze serum immediately. Store and transport at
    -20° C within 7 days. If longer storage is required, store and transport the sample at -70° C for up to 28 days.
    Causes for Rejection:Improperly labeled, incorrect container, contaminated, insufficent quantity, incorrect/delay in transport.
    Reference Range:23 - 60 U/mL
    Additional Information:Low levels of total complement (total hemolytic complement: CH50) may occur during infections, disease exacerbation in patients with systemic lupus erythematosus, and in patients with immune complex diseases such as glomerulonephritis.
     Undetectable levels suggest the possibility of a complement component deficiency. Individual complement component assays are useful to identify the specific deficiency.