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  • Activated Protein C Resistance Panel

    Test Name:Activated Protein C Resistance Panel
    Epic Order Code:LAB846
    CPT Code:85307  
    Specimen(s) Type:Plasma; Full tube required.
    Acceptable Container(s):
    Testing Schedule:Monday - Friday, 7:00am - 3:30pm
    Turn Around Time:STAT: NA
     Routine: 3 - 5 days
    Collection Information:No special patient preparation is required. Obtain specimen by standard collection procedures. If only APC is being collected, draw 5 mL into a red top tube, discard and then collect APC tube. A full tube is required.
    Transport Information:Deliver to lab immediately. All specimens must be signed into the laboratory.
    Reference Clients:If unable to deliver to the lab within 1 hour, centrifuge the specimen for 10 minutes at 3500 RPM to ensure platelet poor plasma. Remove plasma from cells, taking care to avoid the WBC/platelet buffy layer and place into a transport tube. Store and transport at 2-8° C for up to 3 hours. If testing is delayed beyond this, the sample must be stored and transported frozen at -20° C and delivered to lab within 2 weeks.
    Causes for Rejection:Improperly labeled, incorrect container, contaminated, insufficient quantity, incorrect/delay in transport, grossly hemolyzed, clotted, under or over-filled tube.
    Reference Range:< 2.2: Activated Resistance Detected
     > 2.3: APC Resistance not Detected
     Cutoffs may change with lot number. Reference ranges on patient report will reflect lot numbers and cutoffs used at time of testing.
    Additional Information:An elevated Factor VIII, or Lupus anticoagulant, may result in a positive test. Positive modified tests may be a marker for a Factor V Leiden mutant gene, a risk factor for venous thrombosis.