Laser-Capture Microdissection of Human Orbitofrontal Cortex
Craig A. Stockmeier, PhD - Core DirectorCPN Principal Investigator Director, Administrative Core, CPN Director, Postmortem Brain Core, CPN Director, Division of Neurobiology &Human Behavior Professor of Psychiatry and Human Behavior, UMMC Guyton Building, Room G137Phone: (601) 984-5898; fax: (601) 984-5899 E-mail: firstname.lastname@example.org
Gouri Mahajan, MBBS – Core Manager Department of Psychiatry and Human Behavior Guyton Building, Room G131 Phone: (601) 984-6676; fax: (601) 984-5899 Email: email@example.com
Core Collaborators, (CWRU)
Despite the benefits of modern brain imaging in living patients and the numerous animal models of psychiatric illness, there will always be a significant need for the analysis of actual brain tissue postmortem. Studies on postmortem tissues can zero in on individual neurons and their helper cells, neuroglia to assess cellular anatomic features, protein expression and interactions with processes from other individual nerve cells revealing information not attainable from living patients or animal models.
The CPN Postmortem Brain Core is directed by Dr. Craig A. Stockmeier. Dr. Stockmeier has extensive experience in the development and management of a significant postmortem human brain collection in the country devoted specifically to psychiatric neuroscience. This human brain core was funded by the National Institutes of Mental Health from 1989 – 2007 and has been funded by the National Center for Research Resources (NCRR )/National Institute of General Medical Sciences (NIGMS) since 2007.
The brain collection is run in collaboration with the Departments of Psychiatry and Psychology, Case Western Reserve University, Cleveland, OH and the Cuyahoga County Coroner Office, Cleveland. The psychiatric assessment team includes James C. Overholser, PhD and George J. Jurjus, MD. Dr. Overholser, a clinical psychologist, has a long-standing career interest in depressive disorders in adolescents and adults. Dr. Jurjus Director of Inpatient Psychiatry and Detoxification at Cleveland Wade Park VA Hospital has been part of the retrospective diagnostic team since 1997 and provides additional expertise in psychoactive substance use disorders.
Dr. Stockmeier and his collaborators organize all aspects of the brain collection, including storage of tissue samples and accompanying clinical information. CPN principal investigators are provided with high-quality postmortem human brain samples meeting inclusion criteria for their research aims involving psychiatric illnesses, as well as the critical supporting information for the brain tissue. Dr. Stockmeier further advises CPN investigators in the selection and matching of appropriate control and psychiatric subjects for their biological studies.
Postmortem Brain Core
Base Cost = $31.64
Base Cost x 1.495 = $47.30
Base Cost x 1.20 = $37.97
Base Cost x 1.20) x 1.495 = $56.76
2500 North State Street
Jackson, MS 39216
General Information: 601-984-1000
Patient Appointments: 888-815-2005