Associate Professor, Department of BiochemistryCancer Genetics ProgramPhD, Microbiology/Cancer biology, 2000, Louisiana State University Health Sciences Center, New Orleans. Postdoc, 2001-04, Tulane University Health Science Center, New Orleans, LA
Contact information2500 N State St., Room R761Jackson, MS 39216Phone: (601) 815-6832E-mail: email@example.com
Multipotential Mesenchymal Stromal cells (MSCs) hold great potential for treating human degenerative diseases and injuries. Recent, studies regarding the biology of breast cancer stroma indicate that mesenchymal stem cells (MSCs) provide the supportive stroma for solid tumors. The general focus of research in my laboratory is to understand the stromal supportive properties of Mesenchymal Stem Cells (MSCs) from bone marrow and their therapeutic potential. Projects to understand the therapeutic potential of MSCs include (a) epigenetic regulation of MSCs under stress that mimic microenvironment in solid tumors (b) role of microRNA regulation in survival and differentiation of MSCs (c) post translational regulation using autophagic pathway in the survival of MSCs in solid tumor stroma.
A second ongoing project aims to understand the role of MSCs in the osteosarcoma genesis and develop targeted nanotechnology based therapeutics. The projects involve (a) develop affinity tagged therapeutic options using targeted curcumin nanoparticles to osteosarcoma cancer cells using 3D true to life tumor models using patient-derived cancer and stromal cells.
2500 North State Street
Jackson, MS 39216
General Information: 601-984-1000
Patient Appointments: 888-815-2005