Cancer Institute

  • Cancer Research

    One century ago, a cancer diagnosis was a veritable death sentence. Now there are more than 10 million cancer survivors in the United States alone, and many of them are truly and completely cured of these wretched diseases.

    The key to this remarkable turnaround was not simply a matter of scientific discoveries, but the ability of scientists and clinicians to translate newfound knowledge of basic science of cancer into tangible improvements in the ways we prevent, diagnose and treat cancers. Seemingly obscure basic science discoveries, such as the observation in 1914 of mutant fruit flies with notched wings, can lead to new anticancer therapies through diligent research. As an outcome of the research on notched fruit fly wings, we now recognize the significance of the Notch signaling pathway and we are now testing Notch-targeted drugs as part of an experimental breast cancer therapy.

    Our research mission is to build an environment in which imaginative, discovery-oriented ideas will not only flourish, but will also be quickly and efficiently translated into better ways to prevent, detect and cure cancers. The recipe for success calls for teams of talented, highly motivated researchers mixed with cutting-edge technological resources, with a generous dash of clinical collaborations.

    Our research teams and projects are organized into four programs:

    • Cancer genetics
    • Cancer epidemiology
    • Molecular cancer therapeutics
    • Tumor cell biology

    Our research is supported by seven core facilities:

    • Animal imaging core
    • Cancer bioinformatics core
    • Cancer drug discovery core
    • Flow cytometry core
    • Molecular genomics core
    • Shared instrumentation core
    • Tissue microarray/biobanking core