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Chronic physiological assessment of cardiovascular - renal parameters in rodents and large mammals. Analysis of spontaneous fluctuations of blood pressure, heart rate and renal blood flow. Steady-state and dynamic techniques for assessment of baroreflex and renal autoregulatory function. Quantitative modeling of dynamic physiological processes. Determinations of gene expression at mRNA and protein level. Biochemical measurement of reactive species and oxidative stress.
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