Merry L. Lindsey, PhD

Merry L. Lindsey, PhD Professor Director, Jackson Center for Heart Research at UMMC Office: G351-04 Lab: G364/74 Office phone: (601) 815-1329 Lab phone: (601) 984-1824 E-mail: mllindsey@umc.edu

Areas of expertise

• General: Cardiovascular physiology, proteomics
• Specific: Inflammatory and fibrotic mechanisms in the pathogenesis of left ventricular remodeling following myocardial infarction; cardiac aging.

Research methods

Matrix metalloproteinase assays, in vivo myocardial injury models (myocardial infarction and transverse aortic constriction models), murine cardiovascular function analyses, two-dimensional gel electrophoresis, proteomics, histology, immunoblotting, fibroblast tissue culture, macrophage functional assays

Current projects

1. Identifying novel MMP-7 and MMP-9 substrates in post-MI tissues.
2. Using peptidomics to identify novel extracellular matrix signaling pathways altered post-MI.
3. Examining the roles of macrophages and fibroblasts in post-MI remodeling of the left ventricle.
4. Determining the role of aging or periodontal disease on the remodeling process.
5. Discovering novel biomarkers of adverse left ventricular remodeling.

• Biographical sketch  
• Summary of research
• Links to PubMed articles