Whole Body
The whole-body properties are volumes, circulating pools (such as extracellular glucose) and aggregate properties (such as body weight).
- Volumes - Body water, blood, extracellular fluid, interstitial, cell.
- Extracellular - Extracellular fluid volume is the sum of plasma volume, interstitial volume, excess lung water and ascites.
- Pools - Nutrients, hormones, end products. These pools are kept well-mixed by the circulation. For large molecules, the volume of distribution is typically the plasma volume. For smaller molecules, the volume of distribution is typically the extracellular fluid volume. Pools with significant A-V differences, such as oxygen, carbon dioxide and hydrogen ions, are spit into separate arterial and venous pools.
- Aggregate - Body weight, autopsy, maybe others.