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Research Cores


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  • Core B - Bioanalytical, Mass Spectroscopy, Imaging and Histology

     StanLab-SamplesThe Bioanalytical, Mass Spectroscopy, Imaging and Histology Core B provides state-of-the-art centralized research services, including modern facilities, equipment and technical expertise, not currently available in Mississippi but essential for cutting edge obesity, cardiorenal and metabolic disease research. Core B optimizes all assays 
    and core services by consolidating bioanalytical methods and technologies into central facilities in order to perform a larger volume of high-quality measurements at a relatively low cost. Core B provides precise and consistent results using the most up-to-date technology and services needed by COBRE investigators. By providing expertise and major equipment in centralized facilities, Core B provides access to services not feasible for individual labs. The Core also provides support for maintenance of equipment and services, and trains all COBRE investigators in the proper use of equipment located in Core B. Core B faculty and staff will develop new assays as required by the changing needs of the COBRE investigators, improve existing assays, assist with interpretation of results and data, and provide training, technical support, and supervision for COBRE investigators, staff and their tools within the Core. Core B has multiple components including: 
    • Bioanalytical/Mass Spec/HPLC – provides highly specialized proteomics, lipidomics, radioimmunoassay, ELISA assays, and other biochemical analyses. 
    • Imaging/Histology - provides access to state-of–the-art imaging equipment as well as histology, immunohistochemistry, in-situ hybridization and other key services. 
    • Equipment available in Core B includes ABI 4000 and 5500 liquid chromatography/mass spectroscopy systems, imaging systems (confocal microscope, Multi Detector-CT Scanner, Micro-CT Scanner, VisualSonics ultrasound system) and other major equipment.    

    Analytical Assay 

    Mass Spectroscopy 

    Histology

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    Core B Personnel

    Barbara T. Alexander, PhD 
    Core Leader 
    Associate Professor
    Dept. of Physiology & Biophysics
    Univ. of Mississippi Medical Center       
    2500 N. State St.
    Jackson, MS 39216-4505

    Heather A. Drummond, PhD 
    Sub-Leader
    Associate Professor
    Dept. of Physiology & Biophysics
    Univ. of Mississippi Medical Center
    2500 N. State ST.
    Jackson, MS 39216-4505

    Richard J. Roman, PhD 
    Sub-Leader
    Professor and Chair
    Dept. of Pharmacology & Toxicology
    Univ. of Mississippi Medical Center
    2500 N. State St.
    Jackson, MS 39216-4505
    Stanley V. Smith 
    Mass Spectrometry
    Professor
    Dept. of Pharmacology & Toxicology
    Univ. of Mississippi Medical Center
    2500 N. State St.
    Jackson, MS 39216-4505