The broad goal of our research is to dissect the genetic architecture of cancer and other common human diseases such as obesity, diabetes etc. We develop and apply integrative bioinformatics and computational genomics approaches to analysis of high-through "omics", genotype and sequence data. We are particularly focused on biomarker discovery and functional genomics problems involving high-dimensional data sets, such as that obtained from whole genome-transcription profiling, proteomics, large-scale genotyping, and next generation sequencing. The overarching goal of our research is to utilize multiple sources of high-throughput "omics" data to understand the molecular and genetic basis of cancer and other common human diseases and to integrate these data with clinical information to improve human health and reduce health disparities. This involves modeling the complex biological machinery, characterizing the "wiring" diagrams or biological pathways, and elucidating the functional effects of genetic variants, indels, and copy number variants on cis regulatory elements and ncRNAs such as miRNAs.
2500 North State Street
Jackson, MS 39216
General Information: 601-984-1000
Patient Appointments: 888-815-2005