Senior Research Scientist National Center for Natural Products Research Associate Professor of Pharmacology Molecular Cancer Therapeutics Basic Cancer Science at Oxford Program Ph.D., Zoology, 1981, University of Calcutta, West Bengal, India Postdoc, 1985-1986, Florida State University, Tallahassee, FL Post doc, 1991-1993, Medical College of Wisconsin, Milwaukee, WI Post doc, 1997-2002, University of Wisconsin, Milwaukee, WI
Contact informationP.O. Box 1848Faser Hall #313University, MS 38677Phone: (662) 915-7077Fax: (662) 915-5148E-mail: email@example.com
The broad goal of our research is to understand the epigenetic mechanisms involved in cancer development specifically breast cancer and its prevention by bioactive molecules present in natural products. For many years, the search for therapeutic substances for cancer were concentrated on genetic mechanisms, however, it is now clear that deregulation of epigenetic processes are equally important in the propagation of this disease. Moreover, compared to genetic mutation, epigenetic modifications occur frequently and are thought to be reversible; thus the inhibition of these mechanisms could be a potential therapeutic strategy for the treatment of cancer. Our goal is to understand the molecular mechanism(s) by which natural products or bioactive molecules present in the natural products can prevent epigenetic disorders observed in cancer.
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